Occurrence of Urinary Tract Infection in Adolescent and Adult Women of Shanty Town in Dhaka City, Bangladesh

Background: Urinary tract infection (UTI) is one of the most common bacterial infections in Bangladesh. Antimicrobial agents are used for its treatment. The increase in antibiotic resistance among uropathogens is a global problem.Objective: This study was designed to find out the prevalence of UTI, its causative agents and their antimicrobial susceptibility patterns among suspected patients of UTI attending Dhaka Dental College Hospital, Dhaka.Methodology: This cross-sectional study was carried out in Dhaka Dental College Hospital, Dhaka during the period of November 2014 to May 2017. Clinically diagnosed cases of UTI irrespective of age and sex from out-patient department and in-patient department were selected for the purpose of the study. For culture, the urine samples were inoculated on 5% sheep blood agar and MacConkey’s agar media using calibrated loop following standard bacteriological technique. After the incubation period, the plate were examined for bacterial pathogen. The disk diffusion method (Kirby Bauer’s) was used to determine the antimicrobial susceptibility of isolates. Standard inoculums were inoculated on Mueller-Hinton agar and incubated at 37oC for 24 hours.Result: Ninety three urine samples were studied. Among the 93 samples most of them were in the age group of 21 to 30 years. Out of 93 samples, 26 (27.95%) samples were found culture positive. Escherichia coli (92.30%) was found to be the predominant organism. Regarding antimicrobial sensitivity pattern Esch. coli was found to be most sensitive to Imipenem (100%), Amikacin (87.5%), and Nitrofurantoin (83.33%).Conclusion: In conclusion young aged female are commonly suffering from UTI and Escherichia coli is the most common isolated bacteria.Bangladesh Journal of Infectious Diseases, December 2017;4(2):40-44

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“…coli to uroepithelial cells 21 . Other investigators 12,19,[22][23] also reported higher association of Esch. coli.…”

Section: Discussionmentioning

confidence: 79%

Study of Bacterial Pathogens in Urinary Tract Infection and their Antimicrobial Sensitivity Pattern

Parveen

Rahim

2018

Bangladesh J. Infect. Dis.

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“…Publication year 2004-2010 11 (23.9) (Arifeen et al, 2009;Brooks et al, 2005;Haque and Salam, 2010;Khan et al, 2004;Mahbubur et al, 2007;Monjur et al, 2010;Nahar et al, 2004;Rahman et al, 2005;Saha et al, 2009;Shahriar et al, 2010;Shill et al, 2010Shill et al, ) 2011Shill et al, -2014 14 (30.4) (Afroz et al, 2014;Ahmed et al, 2011Ahmed et al, , 2014Akram et al, 2014;Akter et al, 2014;Begum et al, 2013;Chiou et al, 2014;Dutta et al, 2013;Haque et al, 2011;Hossain et al, 2014;Islam et al, 2014;Khan et al, 2013;Rahman et al, 2014;Ud-Din et al, 2013-2018 21 (45.7) (Aftab et al, 2016;Ahmed et al, 2017Ahmed et al, , 2018Ahsan et al, 2016;Akter et al, 2016Akter et al, , 2017Begum et al, 2016;Chakraborty et al, 2016;Chowdhury and Parial, 2015;Haque et al, 2015;Hasan et al, 2016;Islam and Shamsuzzaman, 2015;Jobayer et al, 2017;Khanam et al, 2015;Nazme et al, 2017;…”

Section: Characteristicsmentioning

confidence: 99%

Antibiotic resistance in Bangladesh: A systematic review

Ahmed

Rabbi

Sultana

2019

International Journal of Infectious Diseases

139

105

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Background: Antibiotic resistance (ABR) is a worldwide problem and Bangladesh is a major contributor to this owing to its poor healthcare standards, along with the misuse and overuse of antibiotics. This systematic review was conducted to summarize the present scenario of ABR in Bangladesh, to identify gaps in surveillance, and to provide recommendations based on the findings. Methods: Google Scholar, PubMed, and Bangladesh Journals Online were searched using relevant keywords to identify articles related to ABR in Bangladesh published between 2004 and 2018. Inclusion or exclusion was based on a predefined set of criteria. The resistance of a bacterium to a given drug was presented as the median resistance (MR) and interquartile range (IQR). Results: Forty-six articles were included in this systematic review. Antimicrobial susceptibility testing was performed by disk diffusion method in 82.6% of studies, while the Clinical and Laboratory Standards Institute (CLSI) guidelines were followed in 78.3%. Data regarding the susceptibility testing method, guidelines for interpretation, and source of infection (hospital/community) were absent in 10.9%, 19.6%, and 73.9% of the studies, respectively. A high prevalence of resistance was detected in most tested pathogens, and many of the common first-line drugs were mostly ineffective. Resistance to carbapenems was low in most cases. The presence of extended-spectrum beta-lactamase (ESBL)-producing organisms was indicated by the high resistance to beta-lactams. Methicillin-resistant Staphylococcus aureus (MRSA) was identified in four studies. Three studies reported vancomycin susceptibility of enterococci, and the median susceptibility was 100%. Streptococcus pneumoniae exhibited high susceptibility to penicillin (MR 4%). Resistance data were available from only six out of the 64 districts of Bangladesh. Conclusions: A high prevalence of resistance to most antibiotics was detected, along with major gaps in surveillance and information gaps in the methodological data of the studies (susceptibility testing method, guidelines for susceptibility interpretation, source of infection). Based on the findings, we recommend appropriate initiatives to monitor and control the use of antibiotics, as well as nationwide surveillance following standardized methodologies.

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“…Particularly in low-income countries, the prevalence and occurrence of the multidrugresistant isolates of E. coli are much higher and more common (4). Previous studies have revealed that 69% of the UTIs are caused by E. coli in Bangladesh, where 83-85% of the infected patients are females (21,22). Although many of these women have faced RUTIs in their lifetime, most of them were literally unaware of their reinfections (5) (21,23).…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have revealed that 69% of the UTIs are caused by E. coli in Bangladesh, where 83-85% of the infected patients are females (21,22). Although many of these women have faced RUTIs in their lifetime, most of them were literally unaware of their reinfections (5) (21,23). Previous studies have discovered the failure of the commercial antibiotics against the clinical isolates of E. coli in the major cities of Bangladesh, including Dhaka, Rajshahi, and Sylhet, where 50-70% of drug resistance was noticed from 2010-2015 (24,25).…”

Section: Discussionmentioning

confidence: 99%

The characterization of multidrug resistant type 1 S-fimbriated <i>Escherichia coli </i>from women with recurrent urinary tract infections (RUTIS) in Bangladesh

Hasan¹,

Momtaz²,

Foysal³

et al. 2018

Af J Clin Exp Micro

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The characterization of multidrug resistant type 1 S-fimbriated Escherichia coli from women with recurrent urinary tract infections (RUTIs) in Bangladesh ABSTRACT Background: Escherichia coli is a bacterial species that is most frequently associated with urinary tract infections (UTIs) worldwide. Recurrent UTIs (RUTIs) pose a major threat to health, especially in women. However, studies on the pathogenic potentials of E. coli isolates associated with RUTIs has yet to be done. The present study was designed to characterize the isolates of E. coli from women, suffering from repeated UTIs in Bangladesh. Methods: A total of 15 isolates of E. coli, collected from women with RUTIs in the Sylhet city of Bangladesh, were analyzed by a series of biochemical and molecular tests. Results: The PCR amplification of the mannose-resistant type 1 S-fimbriae gene (sfa1) confirmed all sfa1 + isolates of E. coli. In an antibiogram assay, all the isolates of E. coli were found to be completely resistant to at least five of the ten commercial antibiotics and drug resistance were found to be correlated with the weight of the RUTIs patient. Analysis of the 16S rRNA data of the two most drug-resistant and clinically significant isolates were found to be clustered with the drug-resistant UTI-causing E. coli isolates, circulated in India. Conclusions: This study could pave the way of RUTIs diagnosis and treatment strategy for women in Bangladesh.

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Occurrence of Urinary Tract Infection in Adolescent and Adult Women of Shanty Town in Dhaka City, Bangladesh

Cited by 23 publications

References 35 publications

Study of Bacterial Pathogens in Urinary Tract Infection and their Antimicrobial Sensitivity Pattern

Study of Bacterial Pathogens in Urinary Tract Infection and their Antimicrobial Sensitivity Pattern

Antibiotic resistance in Bangladesh: A systematic review

The characterization of multidrug resistant type 1 S-fimbriated <i>Escherichia coli </i>from women with recurrent urinary tract infections (RUTIS) in Bangladesh

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