Occurrence of intracerebral aneurysm in an HIV-infected child: A case report

Longoria, César Adrián Martínez; Morales-Aguirre, José J.; Villalobos-Acosta, Claudia P.; Gómez-Barreto, Demóstenes; Cashat-Cruz, Miguel

doi:10.1016/j.pediatrneurol.2004.02.008

Cited by 30 publications

(39 citation statements)

References 14 publications

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“…1 In addition, childhood HIV-associated intracranial aneurysmal vasculopathy has been described. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] This report describes an adult HIV-infected woman who had a cerebral infarct caused by aneurysmal dilatation of the arteries in the circle of Willis. To the best of our knowledge, this is the first description of HIV-associated intracranial aneurysmal vasculopathy in an adult with postmortem histopathology.…”

Section: H U M a N I M M U N O D E F Iciency Virus (Hiv) Infec-mentioning

confidence: 99%

Stroke Caused by Human Immunodeficiency Virus–Associated Intracranial Large-Vessel Aneurysmal Vasculopathy

Tipping¹,

Villiers²,

Candy³

et al. 2006

Arch Neurol

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Background: Intracranial aneurysms related to human immunodeficiency virus (HIV) infection have been well described in pediatric patients but not in adults.Objective: To describe a case of intracranial largevessel aneurysmal vasculopathy causing stroke in a 27-year-old HIV-infected woman. Design: Comparison of clinical and histological data with previously published cases.Setting: A referral hospital stroke unit.Patient: A 27-year-old HIV-infected woman presenting with stroke; neuroimaging demonstrated fusiform aneurysmal dilation of the left internal carotid and the left middle cerebral artery and its branches.Results: Autopsy showed degeneration of the elastic lamina, myxoid degeneration, and medial atrophy, causing consequent ectasia of the involved intracranial vessels. Conclusion:Aneurysmal dilation of the intracranial arteries occurs in HIV-infected adults, but the pathogenic role of HIV remains unknown.

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Section: H U M a N I M M U N O D E F Iciency Virus (Hiv) Infec-mentioning

confidence: 99%

Stroke Caused by Human Immunodeficiency Virus–Associated Intracranial Large-Vessel Aneurysmal Vasculopathy

Tipping¹,

Villiers²,

Candy³

et al. 2006

Arch Neurol

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“…In the HIV-infected pediatric populations, the incidence of cerebral aneurysms was reported to be 1.6%, considerably higher than that reported in the non-HIV-infected children. As high as 92% of these pediatric aneurysms were fusiform in nature [8]. The natural history of HIV-associated cerebral aneurysmal disease is less wellknown.…”

Section: Discussionmentioning

confidence: 99%

“…The HIV virus may have a direct damaging effect on the intima of the vessels [8,9]. The HIV viral proteins have been associated with vascular pathology [16,17].…”

Section: Discussionmentioning

confidence: 99%

“…Diagnosis and treatment of cerebral aneurysms in patients with HIV infection or the acquired immunodeficiency syndrome (AIDS) are scantly discussed. The association of HIV/AIDS and cerebral aneurysms has been well documented, especially in the pediatric populations [6][7][8][9]. A recent cohort study indicates that 2.6% of HIV-positive children exhibit neuroimaging findings of cerebrovascular disease, with 63% of those harboring cerebral aneurysms, an incidence higher than in the general population [10].…”

Section: Introductionmentioning

confidence: 99%

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Successful Endovascular Treatment of A Ruptured Mycotic Intracavernous Carotid Artery Aneurysm in an AIDS Patient

et al. 2007

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“…У 36,4% больных детей и 37,5% взрослых пациентов до диагностики аневризм имели место инфаркты мозга. Наличие аневризмы у 45% пациентов детского воз-раста и 25% взрослых не сопровождалось ишемией и геморрагией [43,[53][54][55][56][57][58][59][60][61][62].…”

Section: геморрагические нарушенияunclassified