Occurrence and fate of antibiotics, antimicrobial resistance determinants and potential human pathogens in a wastewater treatment plant and their effects on receiving waters in Nanjing, China

Evaluation of removal of illicit drugs, pharmaceuticals and caffeine in a wastewater reclamation plant and related health risk for non-potable applications

“…Removals of LCN were null or negative in all the treatment stages. It must be remembered that the median concentration in the influent remained close to MRL; furthermore, a recombination of the parent compound might have occurred from their conjugates and metabolites through the different treatment processes, thus increasing the concentration in the outlet which determined high negative removal efficiency, as reported by other authors (Behera et al, 2011;Blair et al, 2015;Chen et al, 2020b;Di Marcantonio et al, 2020b;Verlicchi, 2012).…”

“…A proposed hypothesis to explain this phenomenon is that J o u r n a l P r e -p r o o f conjugated groups of lincomycin metabolites could be broken and converted into lincomycin, causing an increase of the detection frequency and the median concentration in the effluent of the plant (i.e. median effluent concentration equal to 0.01 µg/L and maximum of 0.02 µg/L) (Chen et al, 2020a).…”

Pharmaceuticals in Wastewater Treatment Plants: A Systematic Review on the Substances of Greatest Concern Responsible for the Development of Antimicrobial Resistance

“…Data_extraction.xlsx: Risk of bias, Influents, Effluents, Removals, Risk Assessment and PRs list. References [53][54][55][56][57][58][59] refer to the supplementary material.…”

Electron shuttles enhanced the removal of antibiotics and antibiotic resistance genes in anaerobic systems: A review

“…Nowadays, antibiotics are widely used in medical, breeding, and livestock fields and the dangers associated with antibiotic abuse are increasingly attracting the attention of researchers ( Zhang Q. Q. et al, 2014 ; Zhang Y. J. et al, 2014 ). According to statistics, China produces about 210,000 tons of antibiotics every year ( Luo et al, 2011 ), and about 162,000 tons are used in various practices ( Chen Y. et al, 2020 ). It is worth noting that not all antibiotics ingested into the human body or other living organisms are utilized and about 58% of the drug components are excreted from the body directly and thus into the environment ( Huang et al, 2020 ).…”

“…It is worth noting that not all antibiotics ingested into the human body or other living organisms are utilized and about 58% of the drug components are excreted from the body directly and thus into the environment ( Huang et al, 2020 ). As a result, both the manufacture and consumption of antibiotics lead to a large amount of antibiotic-containing wastewater into the environment ( Zhang et al, 2015 ; Chen Y. et al, 2020 ; Li F. F. et al, 2020 ). A total of 94 antibiotics were found in water bodies and sediments of seven major rivers and four major bay basins in China ( Li et al, 2018 ); 26 antibiotics were detected in surface water of Huangpu River in Shanghai, China ( Pan et al, 2020 ).…”