Occupationally induced pyoderma gangrenosum?

Pyoderma Gangrenosum: The Great Pretender and a Challenging Diagnosis

“…In the literature review presented, a prominent rate of gastrointestinal (38.9%) and hematologic abnormalities (44.4%) was evident. References (all studies reported one patient with hand and finger involvement, except for Huish et al, 5 which reported a series of seven patients): Lucchina et al, 20 Reich et al, 21 Ghosn et al, 12 Zivanovic et al, 10 Mujadzic et al, 22 Weenig et al, 23 Greidanus and Honl, 7 Grange et al, 14 Youker et al, 9 Braun-Falco et al, 24 Manthey and Schissel, 5 Bennett et al, 4,6 Nurre et al, 26 Worley et al, 27 Adam et al, 28 Kitagawa et al, 29 Laurencin and Shoen, 30 Nihei et al, 31 Brown et al, 13 Gasparini et al, 32 Papilion and Bergfield, 33 Young et al, 34 Kanel et al, 35 Schwarz et al, 36 Griffiths and Sundaram, 37 Yusef and Ead, 38 By the time patients present for care of their lesions and analgesics, the red plaques and pustules have already rapidly evolved. On examination, an ulcer with necrosis of a mucopurulent base can be seen with violaceous raised borders.…”

Therapeutic management of pyoderma gangrenosum

“…This concept is supported by the observation that PG is frequently associated with other conditions such as rheumatic diseases, inflammatory bowel diseases (IBDs), and endocrine and hematologic disorders, and by the fact that PG usually responds to systemic corticosteroid therapy (3, 4). PG affects patients at any age, with the highest incidence between ages 25 and 55 years (3, 5, 6). Some reports postulate a predisposition to PG in female patients (7), while others note that the distribution is not sex specific (8, 9).…”