Occupational Risk of Blood-Borne Viruses in Healthcare Workers: A 5-Year Surveillance Program

Baldo, Vincenzo; Floreani, Annarosa; Vecchio, Luigino Dal; Cristofoletti, Marco; Carletti, Maristella; Majori, Silvia; Tommaso, Angela Di; Trivello, R.

doi:10.1086/502059

Cited by 47 publications

(34 citation statements)

References 10 publications

(7 reference statements)

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“…Low rate of positive for HBsAg and anti-HCV HCWs was also found in different studies. In Italy, HBsAg and anti-HCV positivity was found in 0.4% and 0.8% HCWs respectively [15]. A study conducted in Turkey, where anti-HCV seroprevalence in HCWs was compared with one found in blood-donors as a control group revealed that among 702 employees, anti-HCV antibodies were found only in 0.3% of the although it wasn't a part of a study.…”

Section: Discussionmentioning

confidence: 97%

Hepatitis B and C infection: Is it a problem in Polish healthcare workers?

Rybacki¹,

Piekarska²,

Wiszniewska³

et al. 2013

International Journal of Occupational Medicine and Environmental Health

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Objectives: Hepatitis B (HBV) and C viruses (HCV) are among the most frequent blood borne pathogens. According to WHO, 5% of healthcare workers (in central Europe), are exposed to at least one sharps injury contaminated with HBV per year, 1,7% -contaminated with HCV. Aims: The aims of the study were to determine prevalence of HCV and HBV infections, vaccination efficacy against hepatitis B and usefulness of alanine aminotransferase (ALT) testing in prophylactic examinations in healthcare workers (HCWs). Material and Methods: In a group of 520 healthcare workers, a survey, laboratory and serologic tests such as ALT, HBsAg, anti-HBs, anti-HBcT and anti-HCV were carried out. Results: The study revealed a low rate of workers with presence of HBsAg and anti-HCV (1,2% and 0,8% respectively). Anti-HBcT was found in 99 subjects (19%) without a significant association with experiencing an occupational percutaneous injury. Being vaccinated against HBV was declared by 90% of the subjects. There was no relationship between ALT level rise and positive HBsAg, anti-HCV and anti-HBcT tests. Conclusion: A seroprevalence of HBV and HCV markers in HCWs found in the study is low and similar to the one found in general population. Current or past hepatitis B infections were independent of needle stick injuries. Vaccination against HBV coverage, although found to be high, should improve to 100%. Occupational prophylactic medical examinations found performing ALT test (obligatory in Poland for HCWs) not helpful. It seems that determination of anti-HBcT and anti-HCV status would be essential in pre-employment medical examinations.

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Section: Discussionmentioning

confidence: 97%

Hepatitis B and C infection: Is it a problem in Polish healthcare workers?

Rybacki¹,

Piekarska²,

Wiszniewska³

et al. 2013

International Journal of Occupational Medicine and Environmental Health

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“…HCW are at a high risk of HCV infection after occupational exposure (28,30), with the risk of exposure from an HCV-contaminated needle stick injury estimated at 0 to 5%, or almost 10-fold the risk of acquiring HIV from a similar event (7,22). Limited data are available about genotype 4 HCV-specific CMI in seronegative, aviremic HCW working in high-risk environments such as the National Liver Institute (NLI), where HCW provide care for 120,000 outpatients and 15,000 inpatients annually.…”

Section: H Epatitis C Virus (Hcv) Infection Is a Global Health Problemmentioning

confidence: 99%

Hepatitis C Virus-Multispecific T-Cell Responses without Viremia or Seroconversion among Egyptian Health Care Workers at High Risk of Infection

Abdelwahab¹,

Zakaria²,

Sobhy³

et al. 2012

Clin. Vaccine Immunol.

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001). Flow cytometry indicated that both CD4؉ and CD4 ؊ T cells produced IFN-␥. In summary, more than half of Egyptian HCW demonstrated strong HCV multispecific CMI without viremia or seroconversion, suggesting possible clearance of low HCV exposure(s). These data suggest that detecting anti-HCV and viremia to determine past exposure to HCV can lead to an underestimation of the true disease exposure and that CMI response may contribute to the low degree of chronic HCV infection in these HCW. These findings could have strong implications for planning vaccine studies among populations with a high HCV exposure rate. Further studies are needed to determine whether these responses are protective.

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“…Otros autores han encontrado una prevalencia aún menor de fuente positiva para el VIH (2,4% de los pacientes) en una serie de accidentes bioló-gicos declarados en hospitales italianos 23 . En ambos casos, esta disminución podría relacionarse con una disminución del riesgo VIH en los accidentes con sangre u otros fluidos.…”

Section: Tablaunclassified

“…Por sexo, como en la mayoría de los estudios publicados [22][23][24] , las mujeres declaran más accidentes que los hombres (74,9% y 25,1% respectivamente), como se corresponde con la estructura de la población trabajadora, no presentando diferencias estadísticamente significativas.…”

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Accidentes con exposición a material biológico contaminado por VIH en trabajadores de un hospital de tercer nivel de Madrid (1986-2001)

Ilario¹,

Pardo²,

P³

et al. 2004

Rev. Esp. Salud Publica

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Occupational Risk of Blood-Borne Viruses in Healthcare Workers: A 5-Year Surveillance Program

Abstract: Our accurate postexposure follow-up revealed a lack of transmission of HBV, HCV, and HIV.

Cited by 47 publications

References 10 publications

Hepatitis B and C infection: Is it a problem in Polish healthcare workers?

Hepatitis B and C infection: Is it a problem in Polish healthcare workers?

Hepatitis C Virus-Multispecific T-Cell Responses without Viremia or Seroconversion among Egyptian Health Care Workers at High Risk of Infection

Accidentes con exposición a material biológico contaminado por VIH en trabajadores de un hospital de tercer nivel de Madrid (1986-2001)

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