Occupational contact urticaria caused by polyvinylchloride gloves

Contact urticaria to non‐latex synthetic glove material: A case report

“…In another case, type I hypersensitivity to 2,2′‐methylene‐bis‐(4‐methyl‐6‐ tert ‐butylphenol), an antioxidant used in the manufacture of nitrile, has been confirmed, although this diagnosis relied upon the provision of glove constituent information by the manufacturers 3 . Similar to other reported cases of type I hypersensitivity to synthetic gloves, however, the responsible allergen in our patient was not identifiable using standard clinical investigations 4,5 . This case highlights that although rare, type I hypersensitivity to nitrile glove materials can occur and its diagnosis requires a high index of clinical suspicion.…”

Allergic contact dermatitis caused by vinyl gloves: a challenge for clinicians

“…Few cases of contact dermatitis due to vinyl or nitrile have been reported (1-13), as well as cases of allergic contact dermatitis to latex (natural rubber)free gloves (14)(15)(16). As in latex gloves, the allergenic agents in vinyl gloves are often the additives used in their production, such as polymerization agents, preservatives, artificial colourings, and also antioxidants, stabilizers, biocides, formaldehyde (17). Bisphenol A, adipic polyester, mono(2-ethylhexyl) maleate in di-(n-octyl)tin-bis(2-ethylexylmaleate), benzisothiazolinone, formaldehyde and organic pigments, are well known allergens in PVC gloves (1,2,18).…”