Occupational cancers – Epidemiology and certification

Wiszniewska, Marta; Lipińska‐Ojrzanowska, Agnieszka; Witkowska, Anna; Tymoszuk, Diana; Kleniewska, Aneta; Kluszczynski, D.; Walusiak‐Skorupa, Jolanta

doi:10.13075/mp.5893.00620

Cited by 4 publications

(2 citation statements)

References 38 publications

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“…There are cancers known to be strongly associated with environmental factors present in the workplace [ 82 ]. The data are accumulating on the effects of chemicals on the development of PDAC, including exposure to pesticides, asbestos, benzene, and chlorinated hydrocarbons [ 83 ].…”

Section: Occupational Exposure and Physical Factorsmentioning

confidence: 99%

Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors

Michalak

Małecka-Wojciesko

2023

JCM

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This study aims to summarize the modifiable risk factors for pancreatic ductal adenocarcinoma (PDAC) that have been known for a long time, as well as information from the most recent reports. As a cancer with a late diagnosis and poor prognosis, accurate analysis of PDAC risk factors is warranted. The incidence of this cancer continues to rise, and the five-year survival rate is the lowest with respect to other tumors. The influence of cigarette smoking, alcohol consumption, and chronic pancreatitis in increasing the risk of pancreatic ductal adenocarcinoma is continually being confirmed. There are also newly emerging reports relating to the impact of lifestyle, including physical activity, the gut and oral microbiome, and hepatotropic viruses. A precise understanding of PDAC risk factors can help to identify groups of high-risk patients, and this may contribute to population awareness and education as well as earlier diagnoses with possible better treatment outcomes.

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Section: Occupational Exposure and Physical Factorsmentioning

confidence: 99%

Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors

Michalak

Małecka-Wojciesko

2023

JCM

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“…The etiology of neoplastic diseases is complex and multifaceted, conditioned by both external (environmental) and internal factors [4]. It has been shown that some behavioral and psychosocial factors (including stress and depression) as well as genetic predispositions may contribute to the development and progression of neoplastic diseases [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Selected platinum complexes in standard and modern anti-cancer therapies

Kopacz-Bednarska

Król

2022

Nowotwory. Journal of Oncology

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The constantly observed increase in the number of cancer cases inspires research aimed at searching for new compounds with anti-cancer potential. In recent years, much research has focused on platinum complexes, especially their anti-cancer properties. Platinum derivatives are characterized by high cytotoxic activity against many types of cancer cells. However, among the numerous developed complexes, only cisplatin, carboplatin and oxaliplatin have found wide application in chemotherapeutic treatment. Nedaplatin, lobaplatin and heptaplatin have also gained recognition, and have been implemented in oncological therapy in Japan, China and Korea. Some of the platinum complexes are still at the stage of pre-clinical and clinical trials. The aim of the research conducted today is to search for platinum compounds that show high pharmacological effectiveness, with clearly limited side effects. In future therapeutic strategies, the possibility of using platinum complexes in conjunction with other chemotherapeutic compounds is being considered, which may contribute to increasing the efficacy of anti-cancer therapy.

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