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Calcifying epithelial odontogenic tumor of the mandible with clear cell component treated by conservative surgery: report of a case with 30 months of follow‐up

Abstract

Signs and symptoms A 44‐year‐old Caucasian woman was referred by her dentist for evaluation and treatment of a cystic lesion in the right mandibular angle. The referring dentist identified this lesion 3 weeks earlier by way a of routine dental radiograph. Medical history and social history The patient reported a chronic swelling of the right cheek caused by a recurrent lymphangioma, which had been surgically removed four times at other institutions. A cutaneous basal cell carcinoma located at the left side of the nose was successfully excised 7 years earlier. The patient didn't take any medication. Oral disease history Before the onset of repeated swelling and food impaction distal to the right second mandibular molar 2‐months ago, the patient did not have any symptoms. On palpation there was a hard and painless induration located at the lateral border of the right angle of the mandible. A panoramic radiograph demonstrated a well‐defined, multilocular radiolucency at the right mandibular angle and enclosing the crown of a deeply impacted third molar. Diagnoses Based on the clinical and radiological findings, the presumptive diagnosis was a calcifying epithelial odontogenic tumor (CEOT). The differential diagnosis included among others calcified odontogenic cyst, ameloblastic fibro‐odontoma, or ossyfying fibroma. The definite, histopathologically confirmed diagnosis was calcifying epithelial odontogenic tumor with clear cell component (CCCEOT). Treatment The CCCEOT was treated by conservative surgery (enucleation). No recurrence was seen 30 months after treatment. This brings one more argument for a conservative surgical approach for the CEOTs/CCCEOTs of limited size.

Calcifying epithelial odontogenic tumor: an immunohistochemical case study

“…According to the latest review literature (Philipsen and Reichart 2000), there were only 181 cases of CEOTs occurring in the intraosseous (170 cases) and extraosseous (11 cases) locations. Subsequently, there have been a small number of CEOTs studied in English language publications (Kumamoto et al 2001;Cheng et al 2002;Anavi et al 2003;Crivelini et al 2003;Solomon et al 2003;Makos and Nikolaidou 2004;Germanier et al 2005;Patino et al 2005;Seim et al 2005;Bornstein et al 2006;Bridle et al 2006).…”