Obviating Endophthalmitis After Cataract Surgery: Excellent Wound Closure Is the Key

Dubey, Rajni; Brettell, Daniel J.; Montfort, Jess; Coroneo, Minas T.; Francis, Ian C.

doi:10.1001/archophthalmol.2011.322

Cited by 7 publications

(6 citation statements)

References 6 publications

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“…A means of closure that is nontoxic, noninflammatory, and nondisruptive to surrounding tissue would be ideal if it did not induce astigmatism, create opacities, or cause neovascularization. 9 , 54 , 55 It would need to be prepared and applied easily, quickly, and efficiently with the ability to secure a watertight seal until re-epithelialization occurs. 9 , 14 , 54 , 55 The ideal product would have to be biocompatible, biodegradable, and transparent while still providing easy visualization during application.…”

Section: Wound Closure Productsmentioning

confidence: 99%

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Cataract surgery and methods of wound closure: a review

Matossian¹,

Makari²,

Potvin³

2015

OPTH

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Clear corneal incisions are routinely used in cataract surgery, but watertight wound closure may not always be achieved, which can increase the risk for anterior chamber fluid egress or ocular surface fluid ingress. A new US Food and Drug Administration-approved ocular sealant appears to have good efficacy in sealing clear corneal incisions; its use may be indicated when wound integrity is in question.

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Section: Wound Closure Productsmentioning

confidence: 99%

“… 8 The concern is that a wound that is not watertight may potentially signify a pathway for pathogen entry into the anterior chamber with each blink or eyelid squeeze. 9 A leaking CCI on the first PO day was associated with a 44-fold increased risk of endophthalmitis. 10 …”

Section: Introductionmentioning

confidence: 96%

Cataract surgery and methods of wound closure: a review

Matossian¹,

Makari²,

Potvin³

2015

OPTH

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“…Ocular signs include conjunctival injection and intraocular inflammation ranging from mild inflammation to severe panophthalmitis with hypopyon and no view to the posterior pole [5]. Wound abnormalities, including leakage and vitreous incarceration, suggest possibility of infectious contamination [7,22]. B-scan ultrasono graphy is a useful tool to help identify vitreous inflammation caused by infection and associated complications of endophthalmitis such as development of choroidals and retinal detachment [23].…”

Section: Background/incidencementioning

confidence: 99%

Postprocedural endophthalmitis: a review

Levison

Mendes

Bhisitkul

2013

Expert Review of Ophthalmology

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The prevalence of postprocedural endophthalmitis has increased in recent years, due in part to a wider range of indications for ophthalmic procedures, better access to treatments and therefore an increase in the overall number of surgical interventions being performed. Although postprocedural endophthalmitis is a rare event, endophthalmitis is always a devastating complication for both the patient and surgeon. Prompt diagnosis and effective treatment are necessary to increase the likelihood of a good visual outcome. In this review, the authors aim to summarize data of postprocedural endophthalmitis as it pertains to cataract extraction, intravitreal injection, vitrectomy, keratoprosthesis placement, corneal transplants, glaucoma surgery, scleral buckle, strabismus surgery and pterygium excision.

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“…Both strategies have their uses and depend on the resulting LR. 4,5 Also, "best" diagnostic performance depends on the testing situation and objective. In a clinical setting, excluding a diagnosis is as important as confirmation.…”

mentioning

confidence: 99%