Obtaining tissues and organs for transplantation and coronavirus infections: a scoping review

Abstract

Objectives: to map the care recommendations available in the literature capable of supporting health professionals’ decision-making in the organ and tissue donation process before the COVID-19 pandemic. Methods: is a nine-step scoping review with searches performed in three databases and an electronic library (Science Direct). Results: 873 publications were retrieved, 15 selected for analysis. All were published in 2020, originating mainly on China, with predominance of original articles. The most frequent recommendations relate to testing to detect SARS-CoV-2 infection for deceased donors (52.6%) and clinical evaluation of potential donors and possible donors (31.6%). Final considerations: it is believed that the recommendations evidenced will support health professionals in the process of donation and organ transplantations to determine interventions for decision-making during the COVID-19 pandemic.

Infectious events in kidney transplant recipients from deceased expanded criteria donors: a prospective cohort

“…Studies that analyze survival, morbidity and mortality in kidney transplant recipients are important to also assess the cause of death in this group of patients. The leading cause of death during the first year of transplantation has an infectious etiology (4)(5)(6) .…”

“…Infectious events are often related to two conditions: patient immunosuppression and environmental exposures (2,(5)(6)(7) . In kidney transplant patients, the rate of infectious events is 49%, and these complications add significant morbidity and mortality for patients, especially in the first year after transplantation (8) .…”