Obstructive sleep apnea in patients with chronic rhinosinusitis with nasal polyps: a cross-sectional study

Migueis, Débora Petrungaro; Lacerda, Glenda Corrêa Borges de; Lopes, Marta B.; Azevedo-Soster, L.M.S.F.; Thuler, L.C.S.; Lemes, Lucas N. A.; Araújo-Melo, Maria Helena de

doi:10.1016/j.sleep.2019.06.006

Cited by 14 publications

(14 citation statements)

References 28 publications

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“…43 Sleep impairments include snoring, fragmented sleep, daytime sleepiness, and obstructive sleep apnea. 44,45 However, research suggests that NPs themselves in CRS do not worsen or increase the risk for sleep problems. Instead, sleep problems associated with CRSwNP may have multifactorial causes, including underlying inflammatory processes.…”

Section: Impact Of Crswnp On Qolmentioning

confidence: 99%

Chronic Rhinosinusitis With Nasal Polyps: Quality of Life in the Biologics Era

Mullol

Azar

Buchheit

et al. 2022

The Journal of Allergy and Clinical Immunology: In Practice

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Section: Impact Of Crswnp On Qolmentioning

confidence: 99%

Chronic Rhinosinusitis With Nasal Polyps: Quality of Life in the Biologics Era

Mullol

Azar

Buchheit

et al. 2022

The Journal of Allergy and Clinical Immunology: In Practice

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“…Patients with CRS report diminished sleep quality and 15% of these patients have formally diagnosed comorbid OSA 12,13 . The exact relationship between CRS and OSA is not fully understood, though inflammation is proposed to play a key role 9,19 . Upper airway collapse in OSA leads to intermittent hypoxia, triggering inflammatory pathways and subsequent endothelial dysfunction.…”

Section: Discussionmentioning

confidence: 99%

“…Inflammation or obstruction within the nose results in obligate oral breathing and can predispose patients to, or worsen existing OSA 13 . Nasal polyposis specifically has demonstrated an effect on upper airway resistance, sleep quality, and AHI both before and after ESS 19 . CRS has been hypothesized to be equally deleterious on sleep quality as OSA alone.…”

Section: Discussionmentioning

confidence: 99%

Sleep Subdomain of the Sinonasal Outcome Test as a Potential Screening Tool for Sleep Apnea in Chronic Rhinosinusitis

et al. 2023

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Objectives: Approximately 20% of patients with chronic rhinosinusitis (CRS) have comorbid obstructive sleep apnea (OSA). Patients with undiagnosed OSA are at high risk for perioperative complications. The Sinonasal Outcomes Test (SNOT-22) Questionnaire is commonly administered to CRS patients, whereas OSA screening tools are less routinely employed. This study compared SNOT-22 sleep subdomain (Sleep-SNOT) scores among non-OSA CRS versus OSA-CRS patients undergoing ESS, and assessed sensitivity, specificity, and diagnostic accuracy of the Sleep-SNOT for OSA screening.Methods: Retrospective review of patients that underwent endoscopic sinus surgery (ESS) for CRS from 2012 to 2021. Patients either carried a reported OSA diagnosis and completed the SNOT-22, or had undocumented OSA status and completed both STOP-BANG and SNOT-22. Demographics, questionnaire scores, and OSA status were collected. A receiver operating characteristic (ROC) curve assessed cutoff scores, sensitivity, and specificity of the Sleep-SNOT for OSA screening.Results: Of 600 patients reviewed, 109 were included. 41% had comorbid OSA. OSA patients had a higher BMI (32.1

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“…The prevalence of NP (4%) is not different from the general adult population (155) Although NP may be the cause and could contribute to symptoms in some patients with OSA, in general it is not associated with increased daytime sleepiness or worse HRQoL (156). NP has not demonstrated a significant impact on COPD and OSA outcomes.…”

Section: Np and Osamentioning

confidence: 96%

Manifesto on united airways diseases (UAD): an Interasma (global asthma association – GAA) document

et al. 2021

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The large amount of evidence and the renewed interest on upper and lower airways involvement in infectious and inflammatory diseases has led Interasma (Global Asthma Association) to take a position on United Airways Diseases (UAD). Starting from an extensive literature review, Interasma excecutive committee discussed and approved this Manifesto developed by Interasma scientific network (INES) members. The manifesto describes the evidence gathered to date and defines, states, advocates, and proposes issues on UAD (rhinitis, rhinosinusitis and nasal polyposis), and concomitant/comorbid lower airways disorders (asthma, chronic obstructive pulmonary disease, bronchiectasis, cystic fibrosis, obstructive sleep apnoea) with the aim of challenging assumptions, fostering commitment, and bringing about change.UAD refer to clinical pictures characterized by the coexistence of upper and lower airways involvement, driven by a common pathophysiological mechanism, leading to a greater burden on patient's health status and requiring an integrated diagnostic and therapeutic plan.The high prevalence of UAD must be taken into account. Upper and lower airways diseases influence disease control and patient's quality of life. Patients with UAD need to have a timely and adequate diagnosis, treatment, and, when recommended, referral for management in a specialized center. Diagnostic testing including skin prick or serum specific IgE, lung function, fractional exhaled nitric oxide (FeNO), polysomnography, allergen-specific immunotherapies, biological therapies and homebased continuous positive airway pressure (CPAP) whenever these are recommended, should be part of the management plan for UAD.Education of medical students, physicians, health professionals, patients and caregivers on the UAD is needed.

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Obstructive sleep apnea in patients with chronic rhinosinusitis with nasal polyps: a cross-sectional study

Cited by 14 publications

References 28 publications

Chronic Rhinosinusitis With Nasal Polyps: Quality of Life in the Biologics Era

Chronic Rhinosinusitis With Nasal Polyps: Quality of Life in the Biologics Era

Sleep Subdomain of the Sinonasal Outcome Test as a Potential Screening Tool for Sleep Apnea in Chronic Rhinosinusitis

Manifesto on united airways diseases (UAD): an Interasma (global asthma association – GAA) document

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