Obstructive Nephropathy in the pig Aspects of renal hemodynamics and hormonal changes during acute unilateral ureteral obstruction

International Scientific Committee of Radionuclides in Nephrourology (ISCORN) Consensus on Renal Transit Time Measurements

“…116 Acute obstruction results in increased pelvic pressure and a decreased renal blood flow. 138 Though it appears reasonable that increased pressure is the cause of renal damage, during chronic dilation, baseline pressure is only marginally (if even) elevated and cannot be used as a diagnostic criterion. [139][140][141][142] Others have suggested that obstructive damage may be due to renal ischemia.…”