International Scientific Committee of Radionuclides in Nephrourology (ISCORN) Consensus on Renal Transit Time Measurements

Durand, Emmanuel; Blaufox, M. Donald; Britton, K. E.; Carlsen, Ove; Cosgriff, P. S.; Fine, Eugene J.; Fleming, John; Nimmon, C.C.; Piepsz, Amy; Prigent, Alain; Šámal, Martin

doi:10.1053/j.semnuclmed.2007.09.009

“…Renal retention time is the time when radiotracer stays in tubulus before it is sent to ureters. Transit time in nonobstructive patients with dilatation is longer when compared to normal patients [8,22]. Studies carried out in recent years show that the evaluation of both prolonged cortical transit time and poor kidney washout is a valuable indicator/marker for patients who can benefit from pyeloplasty [4,29].…”

Section: Discussionmentioning

confidence: 99%

Comparison of two different periods of renal cortical activity ratios in the evaluation of ureteropelvic junction obstruction by dynamic renal scintigraphy

Hasbek¹,

Özdemir²,

Turgut³

et al. 2014

Cumhuriyet Med J

0

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Aim. The aim of this retrospective study is to investigate whether the renal cortical activity at 1st and 20th minutes in renal scintigraphy can be used as a following parameter to determine the presence of obstruction in pediatric patients group with ureteropelvic junction obstruction. Method. The consecutive 322 kidney renograms were included in the study. Standardized diuretic renograms were visually classified into three groups as non-obstructive, obstructive and indetermined according to their responses to the diuretic. In addition, the cortical regions of interest (ROI) were drawn manually at 1st and 20th min for each kidney and the cortical counts were obtained. Apart from this, kidneys were divided into three major sub-groups based on clearance half-time (T1/2); T1/2<10 min was defined as non-obstruction, T1/2>20 min as obstruction and T1/2 with a value between 10 and 20 minutes as an indeterminate result. Afterwards visual obstruction patterns and 1st/20th min. cortical activity ratios were compared. Results. When the cortical activity ratios are compared to visual obstructive pattern(nonobstructive, obstructive and indeterminate); on the Tc99m DTPA renograms the cortical activity ratios which were greater than 82.8% were obstructive, ranging from 59.3% to 82.8% were found indeterminate. On the Tc-99m MAG-3 renograms the cortical activity ratios which were greater than 74.2% were obstructive, ranging from 44.6% to74.2% were found indeterminate. As a result of the comparison of T 1/2 parameter with the obstruction patterns of the kidneys, T1/2 was in indeterminate group in 124 (41.5%) out of 299 kidneys visually evaluated as non-obstructive while in 7 (2.3%) kidneys T1/2 was in obstructive group. In 4 (23.5%) out of 17 kidneys which were visually evaluated as indeterminate, T 1/2 was in normal group, in 5 (29.4%) of them T 1/2 was in indeterminate group and in 8 (47.1%) of the 17 kidneys T1/2 was in obstructive group. Conclusion. We think that the use of 1st/20th min. cortical activity ratios on the diuretic renogram are helpful in establishing a diagnosis of obstruction in pediatric patient group.

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“…Recently the output efficiency (OE) and normalized residual activity (NORA) parameters are recommended in interpretation of renal scintigraphy [7,8]. NORA is remaininig activity in the kidney at given time.…”

Section: Discussionmentioning

confidence: 99%

Comparison of two different periods of renal cortical activity ratios in the evaluation of ureteropelvic junction obstruction by dynamic renal scintigraphy

Hasbek¹,

Özdemir²,

Turgut³

et al. 2014

CMJ

0

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Aim. The aim of this retrospective study is to investigate whether the renal cortical activity at 1st and 20th minutes in renal scintigraphy can be used as a following parameter to determine the presence of obstruction in pediatric patients group with ureteropelvic junction obstruction. Method. The consecutive 322 kidney renograms were included in the study. Standardized diuretic renograms were visually classified into three groups as non-obstructive, obstructive and indetermined according to their responses to the diuretic. In addition, the cortical regions of interest (ROI) were drawn manually at 1st and 20th min for each kidney and the cortical counts were obtained. Apart from this, kidneys were divided into three major sub-groups based on clearance half-time (T1/2); T1/2<10 min was defined as non-obstruction, T1/2>20 min as obstruction and T1/2 with a value between 10 and 20 minutes as an indeterminate result. Afterwards visual obstruction patterns and 1st/20th min. cortical activity ratios were compared. Results. When the cortical activity ratios are compared to visual obstructive pattern(nonobstructive, obstructive and indeterminate); on the Tc99m DTPA renograms the cortical activity ratios which were greater than 82.8% were obstructive, ranging from 59.3% to 82.8% were found indeterminate. On the Tc-99m MAG-3 renograms the cortical activity ratios which were greater than 74.2% were obstructive, ranging from 44.6% to74.2% were found indeterminate. As a result of the comparison of T 1/2 parameter with the obstruction patterns of the kidneys, T1/2 was in indeterminate group in 124 (41.5%) out of 299 kidneys visually evaluated as non-obstructive while in 7 (2.3%) kidneys T1/2 was in obstructive group. In 4 (23.5%) out of 17 kidneys which were visually evaluated as indeterminate, T 1/2 was in normal group, in 5 (29.4%) of them T 1/2 was in indeterminate group and in 8 (47.1%) of the 17 kidneys T1/2 was in obstructive group. Conclusion. We think that the use of 1st/20th min. cortical activity ratios on the diuretic renogram are helpful in establishing a diagnosis of obstruction in pediatric patient group.

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“…MTT and PTT can have an important role in the diagnosis of obstructive uro-and nephropathy [11,12], renovascular hypertension [12][13][14] and in monitoring the function of the transplanted kidney [15,16]. The most common methods used to determine the values of these parameters are based on the deconvolution of renographic curves and blood activity curve.…”

Section: I-oih 99mmentioning

confidence: 99%

Preliminary assessment of interand intraobserver reproducibility, and normative values of renal mean transit time (MTT) and parenchymal transit time (PTT) for 99mTc-etylenodicysteine

Cichocki

¹

,

Surma

²

,

Woźnicki

³

et al. 2015

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International Scientific Committee of Radionuclides in Nephrourology (ISCORN) Consensus on Renal Transit Time Measurements

Cited by 64 publications

References 174 publications

Comparison of two different periods of renal cortical activity ratios in the evaluation of ureteropelvic junction obstruction by dynamic renal scintigraphy

Comparison of two different periods of renal cortical activity ratios in the evaluation of ureteropelvic junction obstruction by dynamic renal scintigraphy

Comparison of two different periods of renal cortical activity ratios in the evaluation of ureteropelvic junction obstruction by dynamic renal scintigraphy

Preliminary assessment of interand intraobserver reproducibility, and normative values of renal mean transit time (MTT) and parenchymal transit time (PTT) for 99mTc-etylenodicysteine

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