Obstructed small bowel ruptured toward the inguinal canal resulting from metastatic colon carcinoma in an irreducible, recurrent inguinal hernia with mesh-plug repair: Report of a case

Solitary Peritoneal Metastasis of Pancreatic Tail Cancer to a Surgical Mesh for Inguinal Hernia Repair

“…The literature search revealed 5 case reports in the English-language medical literature, and the characteristics of the cases, including ours, are summarized in Table 1. [3][4][5][6][7] In 4 of the previous 5 cases, the primary disease was colon cancer (gastric cancer was concurrent in 1 case) and malignant lymphoma in the other case. Four of the reported cases had a solitary recurrence at the hernia repair site, and 1 had lung metastasis.…”

“…4,6 Moreover, floating malignant tumor cell implantation is considered a cause of metastasis to the hernia repair mesh. 5,7 In addition, some inflammatory cytokines and growth factors such as interleukin-1 beta, interleukin-6), tumor necrosis factor-alpha, epidermal growth factor, basic fibroblast growth factor, heparin-binding epidermal growth factor-like growth factor, and 2 spliced variants of vascular endothelial-derived growth factor contribute to cancer cell implantation, adhesion, and growth at the hernia repair site. These inflammatory cytokines and growth factors are thought to be produced by chronic inflammation resulting from hernia repair mesh placement over an extended period.…”

“…A combination of the following search terms was used: “peritoneal metastasis” AND (“inguinal hernia” OR “surgical mesh”). The literature search revealed 5 case reports in the English-language medical literature, and the characteristics of the cases, including ours, are summarized in Table 1 3–7 . In 4 of the previous 5 cases, the primary disease was colon cancer (gastric cancer was concurrent in 1 case) and malignant lymphoma in the other case.…”

“…Direct cancer cell infiltration from the primary tumor to the hernia mesh has been reported as a possible cause, especially for colon cancer exposed to the peritoneum 4,6 . Moreover, floating malignant tumor cell implantation is considered a cause of metastasis to the hernia repair mesh 5,7 . In addition, some inflammatory cytokines and growth factors such as interleukin-1 beta, interleukin-6), tumor necrosis factor-alpha, epidermal growth factor, basic fibroblast growth factor, heparin-binding epidermal growth factor–like growth factor, and 2 spliced variants of vascular endothelial-derived growth factor contribute to cancer cell implantation, adhesion, and growth at the hernia repair site.…”

Metastatic Sigmoid Colon Cancer Presented as Incarcerated Inguinal Hernia – Case Report

“…Microscopic evaluation should be done for abnormal tissue discovered at surgery or at the pathology ward, which is suggestive of an underlying disease process. The decision to submit a hernia sac for histology may be left to the discretion of the surgeon [8,11].…”