Observations on a Patient With the Malignant Carcinoid Syndrome

Kirkland, James A.; Cass, Rosemary; Lowe, Katherine; Soutar, S. F.

doi:10.1136/jcp.12.4.362

Cited by 8 publications

(3 citation statements)

References 23 publications

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“…The fuchsin-miller method of Slidders (1961a) COMMENT The method as described above with the full degreasing process shows a rapid removal of the phloxin from the collagen, from the erythrocytes, and largely from smooth muscle before there is any serious extraction of the phloxin from fibrin, keratin, and various intracellular substances (mast cell granules, globular bodies of plasma cells, Paneth granules, coagulated myocardial sarcoplasm, hyalin droplets of renal tubules, phloxinophil inclusions). Variants of this method have been used by Attwood (1958) to show keratin in amniotic embolism and by Kirkland, Cass, Lowe, and Soutar (1959) Studies on the character and staining offibrin solution of Coomassie Fast Yellow GS in cellosolve; in properly fixed tissue the erythrocytes are cleared of all red dye before inclusion bodies show any loss of red. 6 Rinse in cellosolve, xylene, and mount in butyl phthalate styrene.…”

Section: The Yellosolve Methodsmentioning

confidence: 99%

Studies on the character and staining of fibrin

Lendrum¹,

Fraser²,

Slidders³

et al. 1962

Journal of Clinical Pathology

401

165

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Section: The Yellosolve Methodsmentioning

confidence: 99%

Studies on the character and staining of fibrin

Lendrum¹,

Fraser²,

Slidders³

et al. 1962

Journal of Clinical Pathology

401

165

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“…Those interested in the recent paper by Anthony and Drury (1970) might care to refer to an earlier study (Kirkland et al, 1959) of the classic changes adjacent to invasive carcinoids. This curious reaction in the material studied in Dundee seemed in some places to be the formation of new elastica within stromal tissue without relationship to vessels, almost as if 'some product of the tumour has a directly stimulating effect on elastic tissue'.…”

Section: Letter To the Editor Elastic Changes And Carcimoidmentioning

confidence: 99%

A simple high-speed recording colorimeter system.

Tennant¹,

Withey²

1970

J Clin Pathol

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The rapid and continuous increase in microbiological assays requested of the routine clinical laboratory has created physical problems by the sheer number of tubes involved. One of the major difficulties is associated with the reading of large numbers of cultures with conventional instruments.In those assays where it is the rate of growth that is being measured, eg, Lactobacillus casei folate assays, standards and tests should theoretically be measured simultaneously. Therefore, in practice, all the cultures to be compared with one set of standards should be read in the shortest possible time. With commercial colorimeters we have found that to read a batch of 500 cultures took two technicians approximately two hours. The method was very prone to copying errors which were not easily determined and the arithmetical processing of the figures was both time consuming and tiring.In order to alleviate these problems we have devised a simple system which enables large numbers of repetitive readings to be made rapidly with consistent accuracy. Used in conjunction with a vortex mixer over 500 tubes an hour can be read by one person. A foot switch is used to control the flow of samples and the recording of colorimeter readings, leaving both hands free to mix specimens and move the probe. The system (Fig. 1) is made more versatile by using flow cells of different light-path lengths, eg, a 2 mm cell enabled six-day Euglena gracilis vitamin B12 assays to be read undiluted. A simple base-board and graticule chart reader enables results to be calculated rapidly.

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Section: Letter To the Editor Elastic Changes And Carcimoidmentioning

confidence: 99%