Observations about sexual and other routes of SARS‐CoV‐2 (COVID‐19) transmission and its prevention

Tatu, Alin Laurențiu; Nadasdy, Thomas; Nwabudike, Lawrence Chukwudi

doi:10.1111/ced.14274

Cited by 18 publications

(25 citation statements)

References 5 publications

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“…as Demodex folliculorum, may also play a role and act as carriers for the virus under these circumstances. 2 Recently, it has been theorized that Demodex may even be used to augment a potential topical vaccine against the SARS-CoV-2 virus through which the mites may be used to enhance antigenic stimulation within the lipid-rich pilosebaceous unit. 5 The histopathology of the varicella-like lesions observed during coronavirus disease (COVID-19) infections of some patients, which were suggestive of viral infection, also raises the issue of whether the rashes contain the SARS-CoV-2 virus itself or not.…”

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confidence: 99%

Comments on “Does COVID ‐19 influence sexual behaviours?”

Nadasdy¹,

Clătici²,

Barinova³

et al. 2020

Dermatologic Therapy

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confidence: 99%

Comments on “Does COVID ‐19 influence sexual behaviours?”

Nadasdy¹,

Clătici²,

Barinova³

et al. 2020

Dermatologic Therapy

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“…5 As such, we recommend strict hygiene measures be adhered to, especially in people who share close quarters. 6,7 The presence of a viral rash on patients is an especially interesting subject. 8 If such affirmations turn out to be true, this too could potentially be a source of viral contamination between sexual partners.…”

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confidence: 99%

New data about sexually transmitted COVID‐19

Tatu

Nadasdy²,

Nwabudike³

2020

Dermatologic Therapy

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The growing body of literature regarding the coronavirus disease 2019 (COVID-19) pandemic has led to interesting developments elucidating the nature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. With regards to viral shedding in genital secretions, current data point to the fact that genital secretions remain clear of the virus and represent an unlikely route of infection. A recent study conducted by Wu et al on COVID-19-infected pregnant woman attempted to assess the risk of vertical transmission by collecting and testing vaginal secretions for the presence of SARS-CoV-2 in which all 13 patients had no evidence of viral shedding. 1 This seems to be confirmed by Yan et al on a larger series of pregnant women infected with SARS-CoV-2 who again could not find signs of viral presence within the female genital fluids they tested. 2 Both studies must be interpreted cautiously as they exclusively used the genital secretions of pregnant women which are generally more abundant and potentially more dilute. Angiotensin-converting enzyme 2 (ACE-2) receptor is currently accepted to be the main host cell entry receptor target for the SARS-CoV-2, and its presence on Leydig cells in male patients has raised concern over the possibility of viral orchitis and viral shedding through seminal fluid. However, current data suggest that no viral RNA is present in the seminal fluid of SARS-CoV-2-positive males. This can be explained by either the viral load, or the concentration of ACE-2 receptors being too low at the level of the testes. 3 In our own recent publication, we too comment on the poten

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“…17 But the route of SARS-CoV -2 (COVID-19) transmission such as through skin-skin contact, vectors and sexual activity is still under study. 27,28 In conclusion, COVID-19 induced skin changes are one of the manifestations of immune responses to the novel coronavirus. Clinical and pathological characteristics are identified as dermal inflammatory reactions and/or skin vascular injury.…”

Section: Discussionmentioning

confidence: 92%