Observation by MR Imaging of In Vivo Temperature Changes Induced by Radio Frequency Hyperthermia

Hall, Alistair S.; Prior, M.V.; Hand, J. W.; Young, I. R.; Dickinson, Robert

doi:10.1097/00004728-199005000-00021

Cited by 80 publications

(37 citation statements)

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“…In most cases, however, it is difficult to measure accurately the inner body temperature using only these parameters, because it is difficult to measure their values separately, and the temperature dependence of each parameter varies from organ to organ and tissue to tissue (15,19,20).…”

Section: Introductionmentioning

confidence: 99%

A precise and fast temperature mapping using water proton chemical shift

Ishihara

Calderón

Watanabe

et al. 1995

Magnetic Resonance in Med

972

856

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A new temperature measurement procedure using phase mapping was developed that makes use of the temperature dependence of the water proton chemical shift. Highly accurate and fast measurements were obtained during phantom and in vivo experiments. In the pure water phantom experiments, an accuracy of more than +/- 0.5 degrees C was obtained within a few seconds/slice using a field echo pulse sequence (TR/TE = 115/13 ms, matrix = 128 x 128, number of slices = 5). The temperature dependence of the water proton chemical shift was found to be almost the same for different materials with a chemical composition similar to living tissues (water, glucide, protein). Using this method, the temperature change inside a cat's brain was obtained with an accuracy of more than +/- 1 degree C and an in-plane resolution of 0.6 x 0.6 mm. The temperature measurement error was affected by several factors in the living system (B0 shifts caused by position shifts of the sample, blood flow, etc.), the position shift effect being the most serious.

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Section: Introductionmentioning

confidence: 99%

A precise and fast temperature mapping using water proton chemical shift

Ishihara

Calderón

Watanabe

et al. 1995

Magnetic Resonance in Med

972

856

View full text Add to dashboard Cite

show abstract

“…This choice is in full agreement with the technical and clinical considerations outlined in a recent review (17). The PRF method is an alternative to T1-dependent temperature changes (18)(19)(20). This latter method was also studied (21) but discarded for real-time applications as its temporal resolution is limited to several seconds by the need to acquire and reconstruct a full inversion-recovery or saturation-recovery MRI experiment.…”

Section: Original Articlementioning

confidence: 99%

Towards MRI temperature mapping in real time—the proton resonance frequency method with undersampled radial MRI and nonlinear inverse reconstruction

Zhang

Michaelis

Frahm

2017

Quant. Imaging Med. Surg.

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IntroductionRecent developments in MRI provide a new method for real-time imaging (1) which offers so far unsurpassed diagnostic capabilities in a large variety of clinical fields. Respective applications range from cardiac MRI without ECG synchronization and during free breathing (2) to real-time studies of blood flow (3), swallowing (4), dysphagia (5), esophageal functions (6), dynamics of the temporomandibular joint (7), respiration-induced flow of the cerebrospinal fluid (8,9) as well as movements of the articulators during normal speech (10) or brass playing of patients with embouchure dystonia (11). In a technical sense, the method is based on highly undersampled radial gradient-echo sequences in combination with iterative image reconstruction by nonlinear inversion (NLINV) and temporal regularization (1). These new possibilities are expected to vastly broaden the range of clinical MRI and, in particular, to stimulate renewed interest in "interventional MRI", i.e., the use of real-time MRI for monitoring and guiding minimally invasive procedures.In this sense, true "real-time" MRI not only refers to high-speed data acquisitions, but includes (I) online Original ArticleTowards MRI temperature mapping in real time-the proton resonance frequency method with undersampled radial MRI and nonlinear inverse reconstruction

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“…For hydrogen nuclei ( 1 H) or proton MR, they include proton density or thermal equilibrium magnetization, M 0 ; [8,9] spin-lattice or longitudinal relaxation time, T 1 ; [10][11][12][13] spin-spin or transverse relaxation time, T 2 ; [11,14,15] the diffusion coefficient, D; [16,17] and resonance frequency or chemical shift [18,19] where T is absolute temperature, N is the number of protons, γ is the magnetogyric ratio, B 0 is the magnetic flux density of a static magnetic field, h is the Plank constant divided by 2π, and k is the Boltzmann constant. In MR imaging, direct measurement of the exact thermal equilibrium is not possible.…”

Section: Temperature Dependent Mr Parametersmentioning

confidence: 99%

“…The temperature dependence of T 1 varies remarkably among these objects. They [16] compared the temperature dependence of T 1 and the diffusion coefficient D for the agar gel phantom doped with copper sulfate and human calf in vivo. Our experiments [26] on T 1 showed that the temperature dependence of T 1 varies according to the kinds of organ tissues.…”

Section: Spin-lattice Relaxation Time Tmentioning

confidence: 99%

Noninvasive Temperature Monitoring

Kuroda

2016

Hyperthermic Oncology From Bench to Bedside

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Noninvasive thermometry of target tissue is one of the key issues for successful and safe thermal therapy. Although various techniques using X-ray, infrared, photoacoustics, radiometry, impedance, ultrasound, and magnetic resonance imaging (MRI) have been investigated, to date, infrared imaging for skin surface or MRI for cross-sectional temperature distribution is accepted as a tool for clinical use. Since cross-sectional temperature distribution deep inside a human body is important in thermal therapy in general, practically, MRI is the only practical modality applicable for the therapies. Among several intrinsic MR parameters including proton density, spin-lattice relaxation time, spin-spin relaxation time, diffusion coefficient and chemical shift, the chemical shift is known to be the most reliable for temperature imaging in aqueous tissues. Because this parameter can be measured only from the resonance frequency of water protons and hence independent from the other parameters, which are measured based on the intensity of the MR signals. Phase mapping or spectroscopic technique are applicable for measuring and/or imaging distribution of temperature change. For adipose tissue spin-lattice relaxation time of fat may be used.

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Observation by MR Imaging of In Vivo Temperature Changes Induced by Radio Frequency Hyperthermia

Cited by 80 publications

References 0 publications

A precise and fast temperature mapping using water proton chemical shift

A precise and fast temperature mapping using water proton chemical shift

Towards MRI temperature mapping in real time—the proton resonance frequency method with undersampled radial MRI and nonlinear inverse reconstruction

Noninvasive Temperature Monitoring

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