Observance of hygiene and dietary rules and the associated factors among diabetic subjects in Essaouira Province, Morocco: a cross-sectional study

Houguig, Khaoula; Ouzennou, Nadia; Rayadi, Mahassine; Rkha, Samia

doi:10.11604/pamj.2022.41.22.30196

Cited by 2 publications

(2 citation statements)

References 26 publications

(23 reference statements)

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“…For statistical testing, we considered diabetic subjects with high observance as “observant” and those with medium and low observance as “non-observant”. Observance in terms of hygiene and dietary rules was also evaluated ( 22 ).…”

Section: Methodsmentioning

confidence: 99%

Factors influencing therapeutic observance in diabetic subjects in the Province of Essaouira (Morocco): A cross-sectional study

Houguig¹,

Rkha²,

Rayadi³

et al. 2022

Ethiop J Health Sci

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BACKGROUND: Therapeutic observance remains a major problem in managing diabetic subjects, just like in other pathologies treated by medication and lifestyle modification. This study aims to determine the rate of therapeutic observance among diabetic subjects in the province of Essaouira and to identify the factors that influence it.METHODS: A cross-sectional questionnaire survey was conducted among 498 type 1 and 2 diabetic subjects, regularly being checked at different health centers in the province of Essaouira (Morocco).RESULTS: Almost a quarter of the surveyed subjects (23.3%) had poor observance. The results of the binary logistic regression model show that, in order of importance, observance is associated with six factors: Availability and access to medical treatment (Odds Ratio OR: 3 ; 95% CI confidence interval [1.78-5.03]); the side effects related to thetreatment (OR: 2.60 ; 95% CI [1.65-4.09]); the family support (OR:1.58 ; 95% CI [0.95-2.61]); duration of diabetes (OR: 0.55 ; 95% CI [0.34-0.88]); the age (OR: 0.50 ; 95% CI [0.30-0.82]); awareness level about the disease (OR: 0.43 ; 95% CI [0.21-0.90])CONCLUSION: The results of the present study have allowed us to identify several factors that can influence therapeutic observance, that prove necessary to be considered and acted upon.

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Section: Methodsmentioning

confidence: 99%

Factors influencing therapeutic observance in diabetic subjects in the Province of Essaouira (Morocco): A cross-sectional study

Houguig¹,

Rkha²,

Rayadi³

et al. 2022

Ethiop J Health Sci

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“…According to research findings, the prevalence of type 2 diabetes among Moroccan adults, aged 20 and up, ranged from 6.6% in 2000 to 12.4% in 2016. Half of Moroccan diabetics are uninformed about their condition and the serious consequences it can have [2,3].…”

Section: Introductionmentioning

confidence: 99%

Phenolic Profile, Inhibition of α-Amylase and α-Glucosidase Enzymes, and Antioxidant Properties of Solanum elaeagnifolium Cav. (Solanaceae): In Vitro and In Silico Investigations

et al. 2023

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In this study, the chemical composition and the antioxidant and antidiabetic properties of S. elaeagnifolium flower (SEFl), fruit (SEFr), and leaf (SEFe) extracts were investigated in vitro and in silico. HPLC-DAD analysis was used to determine the chemical components. Colorimetric techniques were used to identify polyphenols and flavonoids. The antioxidant capacity was determined using DPPH and TAC assays. The antidiabetic activity was examined using the enzymes α-amylase and α-glucosidase. Molecular docking methods were used to assess the anti-dipeptidyl peptidase IV (DPP-IV) activity. According to HPLC findings, extracts of S. elaeagnifolium flowers, leaves, and fruits are rich in salicylic acid, sinapic acid, chlorogenic acid, naringin, quercetin, quercetin-3-O-beta-glucoside, kaempferol, and chalcone. The IC50 for flower, leaf, and fruit extracts were 132 ± 5.59 μg/mL, 43.19 ± 1.46 μg/mL, and 132 ± 5.59 μg/mL, respectively. The total antioxidant capacity of SEFr, SEFe, and SEFl were determined to be 900.06 ± 4.01 μg AAE/mg, 792.10 ± 6.72 μg AAE/mg, and 681.10 ± 3.02 μg AAE/mg, respectively. Importantly, SEFe, SEFl, and SEFr displayed significant anti-α-amylase activity, with IC50 values of 79.16 ± 2.35 µg/mL, 99.16 ± 1.17 µg/mL, and 40.31 ± 2.04 µg/mL, respectively. The results also showed that SEFr, SEFe, and SEFl all exhibited potent anti-α-glucosidase activity, whose IC50 values were determined to be 20.53 ± 0.37 µg/mL (SEFr), 20.05 ± 0.12 µg/mL (SEFe), and 41.1 ± 1.55 µg/mL (SEFl). Molecular docking of S. elaeagnifolium phenolic compounds in the active site of DPP-IV revealed a strong inhibitory effect, with a glide score ranging from −2.63 to −8.10 Kcal/mol. Notably—with glide scores of −8.10, −6.23, −5.73, and −5.37 Kcal/mol—rutin, quercetin-3-O-beta-glucoside, chalcone, and naringin were the most active molecules against DPP-IV.

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Observance of hygiene and dietary rules and the associated factors among diabetic subjects in Essaouira Province, Morocco: a cross-sectional study

Cited by 2 publications

References 26 publications

Factors influencing therapeutic observance in diabetic subjects in the Province of Essaouira (Morocco): A cross-sectional study

Factors influencing therapeutic observance in diabetic subjects in the Province of Essaouira (Morocco): A cross-sectional study

Phenolic Profile, Inhibition of α-Amylase and α-Glucosidase Enzymes, and Antioxidant Properties of Solanum elaeagnifolium Cav. (Solanaceae): In Vitro and In Silico Investigations

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