Object-oriented computational model building of aircraft flight dynamics and systems

Moormann, Dieter; Mosterman, Pieter J.; Looye, Gertjan

doi:10.1016/s1270-9638(99)80036-4

Cited by 23 publications

(14 citation statements)

References 2 publications

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“…Models have widely been used by decision-makers in other industries including meteorology(17), manufacturing(18), transportation(19), aerospace(20), and finance(21), and sports and rehabilitation(22). Their use to date in public health, however, has not been as extensive(23–25).…”

Section: Discussionmentioning

confidence: 99%

Removing the regional level from the Niger vaccine supply chain

Assi

Brown

Kone

et al. 2013

Vaccine

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Objective Since many of the world’s vaccine supply chains contain multiple levels, the question remains of whether removing a level could bring efficiencies. Methods We utilized HERMES to generate a detailed discrete-event simulation model of Niger’s vaccine supply chain and compare the current four-tier (central, regional, district and integrated health center levels) with a modified three-tier structure (removing the regional level). Different scenarios explored various accompanying shipping policies and frequencies. Findings Removing the regional level and implementing a collection-based shipping policy from the district stores increases vaccine availability from a mean of 70% to 100% when districts could collect vaccines at least weekly. Alternatively, implementing a delivery-based shipping policy from the central store monthly in three-route and eight-route scenarios only increases vaccine availability to 87%. Restricting central-to district vaccine shipments to a quarterly schedule for three-route and eight-route scenarios reduces vaccine availability to 49%. The collection-based shipping policy from district stores reduces supply chain logistics cost per dose administered from US$0.14 at baseline to US$0.13 after removing the regional level. Conclusion Removing the regional level from Niger’s vaccine supply chain can substantially improve vaccine availability as long as certain concomitant adjustments to shipping policies and frequencies are implemented.

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Section: Discussionmentioning

confidence: 99%

Removing the regional level from the Niger vaccine supply chain

Assi

Brown

Kone

et al. 2013

Vaccine

View full text Add to dashboard Cite

show abstract

“…Models have long aided decision making in many other industries, such as meteorology [17], manufacturing [18], transportation [19], aerospace [20], and finance [21], and sports and rehabilitation [22]. By contrast, their use to date in public health has not been as extensive [23–25].…”

Section: Discussionmentioning

confidence: 99%

Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand

Lee¹,

Assi²,

Rookkapan³

et al. 2011

Vaccine

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Introduced to minimize open vial wastage, single-dose vaccine vials require more storage space and therefore may affect vaccine supply chains (i.e., the series of steps and processes entailed to deliver vaccines from manufacturers to patients). We developed a computational model of Thailand’s Trang province vaccine supply chain to analyze the effects of switching from a ten-dose measles vaccine presentation to each of the following: a single-dose Measles-Mumps-Rubella vaccine (which Thailand is currently considering) and a single-dose measles vaccine. While the Trang province vaccine supply chain would generally have enough storage and transport capacity to accommodate the switches, the added volume could push some locations’ storage and transport space utilization close to their limits. Single-dose vaccines would allow for more precise ordering and decrease open vial waste, but decrease reserves for unanticipated demand. Moreover, the added disposal and administration costs could far outweigh the costs saved from preventing open vial wastage.

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“…Since reusability often would be an afterthought, there was no need to ensure a model could be employed in a different context. One manifestation of this lack of reusability would be certain behavioral scenarios (e.g., a failure sequence) to be inherent in the model since these would be the only scenarios of interest to a team of engineers and scientists (e.g., [3]). …”

Section: Introductionmentioning

confidence: 99%

A Peer Reviewed Online Computational Modeling Framework

Mosterman

Bouldin²,

Ruciński

2011

PCEEA

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Abstract-Along with theory and experimentation, computational simulation has become the third pillar of scientific discovery. While in industry computational modeling has seen application at an enterprise-wide level in the context of Model-Based Design, in academia models are typically still limited to isolated use by specialists. Once a project is completed, the intellectual property embodied by the model is lost. To harness the effort spent, a networked repository is proposed that stores peer-reviewed models. These models are evaluated whether they adhere to a set of quality requirements so they capture intrinsic value. This would facilitate the type of multi-disciplinary collaboration that is required to engineer the systems that have emerged and that continue to gain in importance. This work puts forward an outline of such a peer-reviewed online repository.

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Object-oriented computational model building of aircraft flight dynamics and systems

Cited by 23 publications

References 2 publications

Removing the regional level from the Niger vaccine supply chain

Removing the regional level from the Niger vaccine supply chain

Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand

A Peer Reviewed Online Computational Modeling Framework

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