Obesity not associated with severity among hospitalized adults with seasonal influenza virus infection

Abstract

We examined seasonal influenza severity [artificial ventilation, intensive care unit (ICU) admission, and radiographic-confirmed pneumonia] by weight category among adults hospitalized with laboratory-confirmed influenza. Using multivariate logistic regression models, we found no association between obesity or severe obesity and artificial ventilation or ICU admission; however, overweight and obese patients had decreased risk of pneumonia. Underweight was associated with pneumonia (adjusted odds ratio 1.31; 95 % confidence interval 1.04, 1.64).

Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community

“…This observation might be consistent with reports of increased inflammation in models of obesity and influenza and severity of ILI in obese persons. (25)(26)(27)(28)(29)(30) Alternatively, increasing BMI is associated with increased frequency of small airways closure and the resulting increased aerosol generation during airway opening as described above may explain the stronger association of BMI with fine than coarse aerosols and lack of association with NP swabs. (31) Our analysis found a clear separation of factors associated with shedding from the nose and those with shedding into aerosols, especially fine particle aerosols.…”

The impact of pediatric obesity on hospitalized children with lower respiratory tract infections in the United States

“…This study investigated the burden of pediatric obesity on lower respiratory tract infections using a nationally representative database in the US. Referring to the previous studies which suggested the potential associations between obesity and morbidity including acute respiratory distress and bacteremia, we hypothesized that children with obesity who were hospitalized due to lower respiratory tract infections were more likely to require non‐invasive or invasive mechanical ventilation, develop bacteremia or septicemia, and needs greater healthcare costs and longer length of hospital stay, compared with children without obesity.…”

Improving access to immunisation for migrants and refugees: recommendations from a stakeholder workshop

“…About 190,000 permanent migrants (skilled and family visa categories) and 14,000 humanitarian entrants enter Australia each year 2 . In the majority of migrant source countries, the national immunisation programs include fewer vaccines than are listed on the Australian Standard Vaccination Schedule, and coverage is variable 3 . Refugees invariably arrive from countries with disruptions to health infrastructure, including immunisation programs.…”

“…2 In the majority of migrant source countries, the national immunisation programs include fewer vaccines than are listed on the Australian Standard Vaccination Schedule, and coverage is variable. 3 Refugees invariably arrive from countries with disruptions to health infrastructure, including immunisation programs. Primary care and specialist practitioners who see recently arrived migrants and refugees reported a need for catch-up immunisation in these groups.…”