Obesity is a risk factor for exercise‐induced bronchospasm in asthmatic adolescents

Almeida, Anderson Henrique Souza de; Filho, Edil de Albuquerque Rodrigues; Costa, Eduarda Lubambo; Albuquerque, Cláudio Gonçalves de; Sarinho, Emanuel Sávio Cavalcanti; Peixoto, Décio Medeiros; Bianca, Ana Caroline Cavalcanti Dela; Júnior, Marco Aurélio Valois Correia; Rizzo, José Ângelo

doi:10.1002/ppul.24875

Cited by 6 publications

(3 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A group from Brazil evaluated exercise-induced bronchospasm (EIB) using cardiopulmonary exercise testing (CPET) in 146 children of which 22% were obese and 19% were overweight. 21 They found that children who were obese were more likely to have EIB on CPET and took longer to recover after CPET. This study is limited by its retrospective nature, but the standardized exercise testing protocol should have reduced some of the variability.…”

Section: Exercise Obesity and Social Determinants Of Healthmentioning

confidence: 99%

See 1 more Smart Citation

Pediatric Pulmonology 2020 year in review: Asthma

Barber

Loughlin

2021

Pediatric Pulmonology

View full text Add to dashboard Cite

Pediatric asthma is a heterogeneous and common chronic condition with significant morbidity and burden on the healthcare system. Despite advances in the field, the disease has proven to be increasingly complex to diagnose and management strategies are constantly evolving. Studies from 2020 have advanced the field even further, particularly with regard to new methods of diagnosis and monitoring, treatment of severe asthma, modifiable risk factors like exercise and obesity, aerosol delivery, and viral respiratory infections contributing to the development of asthma. Continued studies are needed to improve our care for children with asthma and we look forward to future advances. This article is part of our 2020 "Year in Review" series, in which we summarize publications in major topic areas, in the context of selected literature from other journals relevant to our discipline. K E Y W O R D Saerosol biology, asthma and early wheeze, epidemiology, special dimensions of pulmonary medicine Asthma is a common chronic illness in the pediatric population that can be difficult to both diagnose and treat effectively. Research in 2020 has advanced the field of pediatric asthma within the domains of diagnostic testing and monitoring, disease management, severe asthma and exacerbations, aerosol delivery, lifestyle and social determinants of health, and the effect of early viral infections. This article is part of our 2020 "Year in Review" series, in which we summarize publications in major topic areas, in the context of selected literature from other journals relevant to our discipline.

show abstract

Section: Exercise Obesity and Social Determinants Of Healthmentioning

confidence: 99%

“…A group from Brazil evaluated exercise‐induced bronchospasm (EIB) using cardiopulmonary exercise testing (CPET) in 146 children of which 22% were obese and 19% were overweight 21 . They found that children who were obese were more likely to have EIB on CPET and took longer to recover after CPET.…”

Section: Exercise Obesity and Social Determinants Of Healthmentioning

confidence: 99%

Pediatric Pulmonology 2020 year in review: Asthma

Barber

Loughlin

2021

Pediatric Pulmonology

View full text Add to dashboard Cite

show abstract

“…Souza de Almeida et al [ 66 ] conducted a cross-sectional study on 156 young asthmatics in order to study the correlation between obesity and the risk and severity of exercise-induced bronchospasm in asthmatic children and adolescents. They observed a greater risk of exercise-induced bronchospasm in obese individuals with asthma, compared to non-obese peers.…”

Section: Aetiopathogenesis Of the Bidirectional Relationship Between Obesity And Asthmamentioning

confidence: 99%

An Overview of the Obese-Asthma Phenotype in Children

Fainardi

Passadore

Labate

et al. 2022

IJERPH

View full text Add to dashboard Cite

Asthma is the most common chronic disease in childhood. Overweight and obesity are included among the comorbidities considered in patients with difficult-to-treat asthma, suggesting a specific phenotype of the disease. Therefore, the constant increase in obesity prevalence in children and adolescents raises concerns about the parallel increase of obesity-associated asthma. The possible correlation between obesity and asthma has been investigated over the last decade by different authors, who suggest a complex multifactorial relationship. Although the particular non-eosinophilic endotype of obesity-related asthma supports the concept that high body weight precedes asthma development, there is ongoing debate about the direct causality of these two entities. A number of mechanisms may be involved in asthma in combination with obesity disease in children, including reduced physical activity, abnormal ventilation, chronic systemic inflammation, hormonal influences, genetics and additional comorbidities, such as gastroesophageal reflux and dysfunctional breathing. The identification of the obesity-related asthma phenotype is crucial to initiate specific therapeutic management. Besides the cornerstones of asthma treatment, lifestyle should be optimized, with interventions aiming to promote physical exercise, healthy diet, and comorbidities. Future studies should clarify the exact association between asthma and obesity and the mechanisms underlying the pathogenesis of these two related conditions with the aim to define personalized therapeutic strategies for asthma management in this population.

show abstract