O inquérito eletrocardiográfico

Gonçalves, Julio Cesar de Souza Inácio; Prata, Áluízio; Dias, João Carlos Pinto; Macêdo, Vanize

doi:10.1590/s0037-86822011000800007

Cited by 4 publications

(2 citation statements)

References 14 publications

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“…RBBB isolated or associated with LAFB was detected in 25% of the participants and are the most commonly reported alterations in patients with ChD 9 . In the State of Sergipe, 46.3% of patients with ChD had changes electrocardiographic in the national electrocardiographic survey conducted between 1977 and 1981 10 . In this study, the frequency was higher (60.5%) and similar to that reported in the State of Goiás (63.6%), which was the highest percentage in the survey.…”

Section: American Trypanosomiasis Was First Described By Carlosmentioning

confidence: 99%

Clinical and epidemiological characteristics of Chagas disease in an endemic area of Sergipe State, Brazil

Glass

Santos

Varjão

et al. 2018

Rev. Soc. Bras. Med. Trop.

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Introduction: We evaluated clinical and epidemiological characteristics of Trypanosoma cruzi infection in Sergipe. Methods: In this cross-sectional study, we collected serum samples to identify serological markers of Chagas disease. A questionnaire was used, and electrocardiogram, echocardiogram, chest radiography, and contrast radiography of esophagus and colon were performed. Results: T. cruzi infection seroprevalence was 12.1%, mean age of subjects was 55 years, 90% had an elementary school education, 78.6% were agriculture workers, and 60.5% had electrocardiographic abnormalities. Conclusions: A high prevalence of T. cruzi infection was observed in mostly elderly individuals.

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Section: American Trypanosomiasis Was First Described By Carlosmentioning

confidence: 99%

Clinical and epidemiological characteristics of Chagas disease in an endemic area of Sergipe State, Brazil

Glass

Santos

Varjão

et al. 2018

Rev. Soc. Bras. Med. Trop.

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“…27 Dados de inquérito eletrocardiográfico para DC, conduzido entre 1977 e 1981, apontavam que o estado do Rio Grande do Sul tinha uma população chagásica com menor ocorrência de complicação cardíaca (21,7%), enquanto Goiás e Minas Gerais contavam os correspondentes percentuais em 63,6% e 57,6%, respectivamente. 28 No inquérito sorológico da década de 1990, conduzido entre escolares de até 14 anos de idade, o Rio Grande do Sul apresentou a maior prevalência de casos (0,70%), seguido de Goiás (0,45%). 18 A relevância epidemiológica da doença de Chagas justifica-se pelo fato de estar inserida no grupo de doenças infecciosas classificadas como negligenciadas, atualmente objeto de políticas públicas nacionais de incentivo à investigação, prevenção e controle, bem como ao tratamento.…”

Section: Jurema Corrêa Da Mota E Colaboradoresunclassified

Estimativa de taxa de mortalidade e taxa de incidência de sequelas cardíacas e digestivas por doença de Chagas no Brasil, 2008

Mota¹,

Campos²,

Schramm³

et al. 2014

Epidemiol. Serv. Saúde

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Benznidazole decreases the risk of chronic Chagas disease progression and cardiovascular events: A long-term follow up study

et al. 2021

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Background Chagas disease (CD) remains an important endemic disease in Latin America. However, CD became globalized in recent decades. The majority of the chronically infected individuals did not receive etiologic treatment for several reasons, among them the most conspicuous is the lack of access to diagnosis. The impact of trypanocidal treatment on CD chronic phase, without cardiac involvement (indeterminate form ICF), is yet to be determined. We aimed to evaluate the effect of trypanocidal treatment with benznidazole (BZN) on the rate of progression to Chagas heart disease in patients with ICF. Methods This is a retrospective cohort observational study including patients with ICF treated with BZN and compared to a group of non-treated patients matched for age, sex, region of origin, and the year of cohort entry. We reviewed the medical charts of all patients followed from May 1987 to June 2020 at the outpatient center of the Evandro Chagas National Institute of Infectious Diseases (INI) of the Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil. Patients’ follow-up included at least one annual medical visit and one annual electrocardiogram (ECG). Echocardiographic exams were performed at baseline and during the follow-up. Disease progression from ICF to cardiac form was defined by changes in baseline ECG. Cumulative incidence and the incidence rate were described in the incidence analysis. Cox proportional hazards models were used to estimate hazard ratios and 95% confidence intervals for the association between BZN and CD progression, cardiovascular events or death. Findings One hundred and fourteen treated patients met the study inclusion criteria. A comparison group of 114 non-treated patients matched for age, sex, region of origin, and the year of cohort entry was also included, totalizing 228 patients. Most patients included in the study were male (70.2%), and their mean age was 31.3 (+7.4) years. Over a median follow-up of 15.1 years (ranging from 1.0 to 32.4), the cumulative CD progression incidence in treated patients was 7.9% vs. 21.1% in the non-treated group ( p = 0.04) and the CD progression rate was 0.49 per 1.000 patients/year in treated patients vs. 1.10 per 1.000 patients/year for non-treated patients ( p = 0.02). BZN treatment was associated with a decreased risk of CD progression in both unadjusted (HR 0.46; 95%CI 0.21 to 0.98) and adjusted (HR 0.43; 95%CI 0.19 to 0.96) models and with a decreased risk of occurrence of the composite of cardiovascular events only in the adjusted (HR 0.15; 95%CI 0.03 to 0.80) model. No association was observed between BZN treatment and mortality. Interpretation In a long-term follow-up, BZN treatment was associated with a decreased incidence of CD progression from ICF to the cardiac form and also with a decreased risk of cardiovascular events. Therefore, our results indicate that BZN treatment for C...

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O inquérito eletrocardiográfico

Cited by 4 publications

References 14 publications

Clinical and epidemiological characteristics of Chagas disease in an endemic area of Sergipe State, Brazil

Clinical and epidemiological characteristics of Chagas disease in an endemic area of Sergipe State, Brazil

Estimativa de taxa de mortalidade e taxa de incidência de sequelas cardíacas e digestivas por doença de Chagas no Brasil, 2008

Benznidazole decreases the risk of chronic Chagas disease progression and cardiovascular events: A long-term follow up study

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