2009
DOI: 10.1245/s10434-009-0630-2
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Nutritional Support with Endoluminal Stenting During Neoadjuvant Therapy for Esophageal Malignancy

Abstract: Esophageal stenting in the neoadjuvant setting offers improved results compared with feeding tubes both in maintaining preoperative nutrition and in tolerance of neoadjuvant chemoradiotherapy. Future protocols of patients treated with multimodal therapy for cancer of the esophagus should investigate the potential therapeutic benefit of using removable silicone esophageal stents as an alternative to feeding tubes.

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Cited by 58 publications
(44 citation statements)
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“…Preoperative malnutrition and prognosis after neoadjuvant chemotherapy followed by subsequent esophagectomy with stenosis during preoperative chemotherapy has been shown effective in maintaining preoperative nutrition (18,19). In addition, ghrelin administration may help maintain body weight and minimize the deterioration of nutritional status during chemotherapy (20).…”
Section: Editorialmentioning
confidence: 99%
“…Preoperative malnutrition and prognosis after neoadjuvant chemotherapy followed by subsequent esophagectomy with stenosis during preoperative chemotherapy has been shown effective in maintaining preoperative nutrition (18,19). In addition, ghrelin administration may help maintain body weight and minimize the deterioration of nutritional status during chemotherapy (20).…”
Section: Editorialmentioning
confidence: 99%
“…Patients with esophageal cancer who are obstructed or experiencing dysphagia will likely need assistance with nutrition pre-operatively during neoadjuvant therapy. Compared with enteral feeding with a feeding jejunostomy, oral alimentation after placement of a covered silicone stent results in better relief of dysphagia, higher performance status, better tolerance of chemoradiotherapy, and better quality of life (12)(13)(14).…”
Section: Preoperative Evaluationmentioning
confidence: 99%
“…Patients with esophageal cancer who are obstructed or experiencing dysphagia will likely need assistance with nutrition pre-operatively during neoadjuvant therapy. Compared with enteral feeding with a feeding jejunostomy, oral alimentation after placement of a covered silicone stent results in better relief of dysphagia, higher performance status, better tolerance of chemoradiotherapy, and better quality of life (12)(13)(14).After completion of neoadjuvant chemoradiotherapy, restaging PET-CT should be performed to rule out progression of disease or metastasis. Patients who have persistent disease or show a complete or partial response based on the lesion's FDG avidity on PET-CT are scheduled for esophagectomy 6-10 weeks after completion of neoadjuvant therapy.…”
mentioning
confidence: 99%
“…31 Covered esophageal stents may be temporarily placed to relieve dysphagia, whereas patients undergo neoadjuvant therapy, thereby acting as a bridge to surgery. [32][33][34][35] Both plastic [32][33][34] and metal stents 35 have been used for this indication, which is yet to be approved by the U.S. Food and Drug Administration. After successful stent placement, improvement in dysphagia scores and nutritional status was reported in almost all patients.…”
Section: Esophageal Stentsmentioning
confidence: 99%
“…Stent migration is a concern, particularly after initiation of neoadjuvant therapy, and has been reported in 24% to 46% of patients. [32][33][34][35] Elective removal of the stent has been attempted to reduce the migration risk. 36 …”
Section: Esophageal Stentsmentioning
confidence: 99%