Nutritional status and growth in juvenile rheumatoid arthritis

Bacon, Melanie C.; White, Patience H.; Raiten, Daniel J.; Craft, Neal E.; Margolis, Sam A.; Levander, Orville A.; Taylor, Martha; Lipnick, Robert; Sami, Seppideh

doi:10.1016/0049-0172(90)90022-8

Cited by 57 publications

(32 citation statements)

References 33 publications

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“…Our results (Table 1) confirm previous work (Bacon et al, 1990), and the type of disease (pauci=poly=systemic) reported by other authors (Bacon et al, 1990;Haugen et al, 1992). Nevertheless, the majority of individuals of the control group and of the JRA patients, with and without disease activity, did not reach the RDA recommendation for both elements.…”

Section: Discussionsupporting

confidence: 90%

“…Our results regarding the increased serum copper level in the JRA group in relation to the control group, controlled for age (Table 5), are consistent with previous studies (Bacon et al, 1990;Haugen et al, 1992;Strano et al, 1995). Ninety percent of the serum copper is incorporated to the ceruloplasmin (Rosenstein & Caldwell, 1999), which is one of the main extracellular antioxidants (Kiziltunc et al, 1998).…”

Section: Serum Coppersupporting

confidence: 91%

“…These results agree with those of Bacon et al (1990) when comparing polyarticular patients with healthy children. When the comparison is between the pauci and polyarticular types, our results are not in accordance with those of Haugen et al (1992).…”

Section: Serum Coppersupporting

confidence: 90%

“…On the other hand, the acute or chronic inflammation induces metabolism alterations of these minerals, determining alterations in their serum and tissue levels (Soylak & Kirnap, 2001), as well as triggering other nutritional impairments (Gó mez-Vaquero et al, 2001). However, there are few studies about the copper and zinc serum levels in juvenile rheumatoid arthritis ( JRA; Makela et al, 1984;Honkanen et al, 1989;Bacon et al, 1990;Haugen et al, 1992;Strano et al, 1995).…”

Section: Introductionmentioning

confidence: 99%

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Copper and zinc intake and serum levels in patients with juvenile rheumatoid arthritis

et al. 2003

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Objective: To evaluate the copper and zinc intake and serum levels in patients with juvenile rheumatoid arthritis (JRA), considering the pauci and polyarticular types, the disease activity and duration, the number of inflamed joints and the use of corticosteroids therapy. Design: Cross-sectional study with control group. Setting: Outpatients of the pediatric rheumatology public health clinic, of the Universidade Federal de São Paulo=Escola Paulista de Medicina, Brazil. Subjects: Forty-one patients with JRA were evaluated and 23 patients' brothers, as a control group. Interventions: Copper and zinc intake evaluation by Food Register method. Copper and zinc serum levels by atomic absorption spectrophotometry. Results: The disease activity did not determine difference in copper (P ¼ 0.624) and zinc (P ¼ 0.705) intake, being predominantly below the Recommended Dietary Allowances. The serum copper in relation to control was statistically greater (P ¼ 0.018), showing that the number of inflamed joints is statistically significantly related with its variation (P ¼ 0.001). The serum zinc was not different either in relation to control (P ¼ 0.940) or to the disease characteristics. Conclusions: The evaluation of copper intake seems to be of fundamental importance. It may influence the efficiency of the organic serum response. More research is needed to indicate, with security, adequate zinc intake.

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Section: Discussionsupporting

confidence: 90%

Section: Serum Coppersupporting

confidence: 91%

Section: Serum Coppersupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

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Copper and zinc intake and serum levels in patients with juvenile rheumatoid arthritis

et al. 2003

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“…Plasma IGF-1 is low in malnutrition (32), when basal levels of GH may be raised (33). Nutritional status may be suboptimal in JRA (1,34), and perhaps, increased catabolism and/or impaired protein synthesis may occur. An analogous condition is critical illness with sepsis, in which there is impaired production of IGF-1 in response to rHuGH (35).…”

Section: Discussionmentioning

confidence: 99%

Juvenile rheumatoid arthritis. Effects of disease activity and recombinant human growth hormone on insulin‐like growth factor 1, insulin‐like growth factor binding proteins 1 and 3, and osteocalcin

Davies

Sandoval

Reeve

et al. 1997

Arthritis & Rheumatism

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Objective. To investigate possible mechanisms of growth impairment in children with juvenile rheumatoid arthritis (JRA). Methods.Eighteen prepubertal children with JRA and growth retardation received recombinant human growth hormone (rHuGH) for 1 year. Growth hormone profiles over 24 hours were obtained before treatment in 12 patients; the levels did not differ from those in "short normal" children. Levels of insulin-like growth factor 1 (IGF-1), IGF binding proteins (IGFBPs) 1 and 3, insulin, osteocalcin, and C-reactive protein (CRF'), as well as the erythrocyte sedimentation rate were measured serially. Pretreatment levels were compared with control levels.Results. In JRA patients, IGF-1, IGFBP-3, and osteocalcin levels were significantly lower and insulin levels significantly higher than those in controls, but there was no significant difference in the level of IGFBP-1. With rHuGH treatment, height velocity and mean levels of IGF-1, osteocalcin, and insulin increased

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The Challenge of Caring for Indigent Children With Rheumatologic Diseases

Miller

White

1991

Arch Pediatr Adolesc Med

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Nutritional status and growth in juvenile rheumatoid arthritis

Cited by 57 publications

References 33 publications

Copper and zinc intake and serum levels in patients with juvenile rheumatoid arthritis

Copper and zinc intake and serum levels in patients with juvenile rheumatoid arthritis

Juvenile rheumatoid arthritis. Effects of disease activity and recombinant human growth hormone on insulin‐like growth factor 1, insulin‐like growth factor binding proteins 1 and 3, and osteocalcin

The Challenge of Caring for Indigent Children With Rheumatologic Diseases

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