Nutritional Factors In Cataract

Bunce, G. E.

doi:10.1146/annurev.nutr.10.1.233

Cited by 20 publications

(28 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The enzyme aldose-reductase converts glucose to sorbitol, which increases the osmotic pressure in the lens; this causes water to flow in, and results in clouding. 4 Cataract formation in plains viscachas might be accelerated by an increased aldosereductase activity in the lens similar to degus with type 2 diabetes mellitus. 7 Diabetic cataract is always bilateral.…”

Section: Discussionmentioning

confidence: 99%

“…30 In humans, senescent cortical cataracts are generally associated with derangement of electrolyte and water balance. 8 Further nutritional etiologies for cataract are described in a review of Bunce et al 4 i.e. a riboflavin deficient diet for carnivores such as young cats (Felis catus), 13 chinook salmons (Oncorhynchus tshawytscha) 15 , rainbow trout (Oncorhynchus mykiss) 17 and for omnivores like young rats (Rattus norvegicus) 9 and young pigs (Sus scrofa domestica).…”

Section: Discussionmentioning

confidence: 99%

“…a riboflavin deficient diet for carnivores such as young cats (Felis catus), 13 chinook salmons (Oncorhynchus tshawytscha) 15 , rainbow trout (Oncorhynchus mykiss) 17 and for omnivores like young rats (Rattus norvegicus) 9 and young pigs (Sus scrofa domestica). 25 Prenatal deprivation of vitamin E can also lead to cataract formation in the omnivorous turkey (Meleagris gallopavo) 4 and the rat 4 . Cataract is not described in conjunction with vitamin C deficiency, but scorbutic guinea pigs (Cavia porcellus) which were fed a high-galactose diet CATARACTS IN VISCACHAS developed cataract sooner than their ascorbate-supplemented littermates.…”

Section: Discussionmentioning

confidence: 99%

“…Cataract is not described in conjunction with vitamin C deficiency, but scorbutic guinea pigs (Cavia porcellus) which were fed a high-galactose diet CATARACTS IN VISCACHAS developed cataract sooner than their ascorbate-supplemented littermates. 4 Deficiencies of some essential aminoacids may also have a cataractogenic effect. Deficiency of phenylalanine 21 , tryptophan 4 , and histidine 21 causes cataract in the omnivorous rat.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Occurrence of Cataract and Fatty Liver in Captive Plains Viscachas (Lagostomus maximus) in Relation to Diet

Gull¹,

Steinmetz²,

Clauß

et al. 2009

Journal of Zoo and Wildlife Medicine

View full text Add to dashboard Cite

Occurrence of cataract and fatty liver in captive plains viscachas (Lagostomus maximus) in relation to diet Abstract An increased incidence of cataract and fatty liver in plains viscachas (Lagostomus maximus) was noted for many years at the Zurich Zoo. Based on elevated serum fructosamine and glucose, diabetes mellitus was diagnosed, and these parameters normalized when the diet of the animals was changed from a low-fiber to a high-fiber diet. Here, we evaluate 177 necropsy reports from before and after the diet change for the incidence of cataracts and fatty liver. Sixteen of 56 animals (29%) that were born before the diet change developed cataract. In contrast, only two of 121 animals (1.65%) that were born after the diet change developed cataracts. The prevalence of cataract and fatty liver in animals born after the diet change (1% and 0%, respectively) was significantly lower than in animals born before (9% and 6%, respectively) the diet change. The results suggest that the plains viscachas at Zurich Zoo were affected by an alimentary induced diabetes mellitus (type 2) before the diet was changed. Clauss (e-mail: mclauss@vetclinics.uzh.ch) CATARACTS IN VISCACHASAbstract: An increased incidence of cataract and fatty liver in plains viscachas (Lagostomus maximus) was noted for many years at the Zurich Zoo. Based on elevated serum fructosamine and glucose, diabetes mellitus was diagnosed, and these parameters normalized when the diet of the animals was changed from a low-fiber to a high-fiber diet. Here, we evaluate 177 necropsy reports from before and after the diet change for the incidence of cataracts and fatty liver. Sixteen of 56 animals (29%) that were born before the diet change developed cataract.In contrast, only two of 121 animals (1.65%) that were born after the diet change developed cataracts. The prevalence of cataract and fatty liver in animals born after the diet change (1% and 0%, respectively) was significantly lower than in animals born before (9% and 6%, respectively) the diet change. The results suggest that the plains viscachas at Zurich Zoo were affected by an alimentary induced diabetes mellitus (type 2) before the diet was changed.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Occurrence of Cataract and Fatty Liver in Captive Plains Viscachas (Lagostomus maximus) in Relation to Diet

Gull¹,

Steinmetz²,

Clauß

et al. 2009

Journal of Zoo and Wildlife Medicine

View full text Add to dashboard Cite

show abstract

“…Laboratory and animal data point to a causal role for oxidative mechanisms and suggest a possible beneficial role for antioxidant nutrients, especially vitamin E, in delaying ARC onset and progression (4)(5)(6) . Vitamin E, a lipid-soluble antioxidant concentrated in lens fibres and membranes, is postulated to inhibit ARC formation by reducing photoperoxidation of lens lipids and stabilizing lens cell membranes (7,8) . A number of epidemiological studies (9)(10)(11)(12)(13)(14)(15) generally support an inverse association between vitamin E and the risk of ARC.…”

mentioning

confidence: 99%

Vitamin E and risk of age-related cataract: a meta-analysis

Zhang¹,

Jiang²,

Xie³

et al. 2015

Public Health Nutr.

View full text Add to dashboard Cite

Objective: We conducted a meta-analysis to evaluate the relationship between vitamin E and age-related cataract (ARC). Design: The fixed-or random-effect model was selected based on heterogeneity. Meta-regression was used to explore potential sources of between-study heterogeneity. Publication bias was evaluated using Begg's test. The dose-response relationship was assessed by a restricted cubic spline model. Setting: Relevant studies were identified by a search of PubMed and the Cochrane Library to May 2014, without language restrictions. Subjects: Studies involved samples of people of all ages. Results: Dietary vitamin E intake, dietary and supplemental vitamin E intake, and high serum tocopherol levels were significantly associated with decreased risk of ARC, the pooled relative risk was 0·73 (95 % CI 0·58, 0·92), 0·86 (95 % CI 0·75, 0·99) and 0·77 (95 % CI 0·66, 0·91), respectively. Supplemental vitamin E intake was non-significantly associated with ARC risk (relative risk = 0·92; 95 % CI 0·78, 1·07). The findings from dose-response analysis showed evidence of a non-linear association between dietary vitamin E intake and ARC. The risk of ARC decreased with dietary vitamin E intake from 7 mg/d (relative risk = 0·94; 95 % CI 0·90, 0·97). Conclusions: The findings of the meta-analysis indicated that dietary vitamin E intake, dietary and supplemental vitamin E intake, and high level of serum tocopherol might be significantly associated with reduced ARC risk.

show abstract

Doctor, What Vitamins Should I Take for My Eyes?

Mares

Rowe²,

Blodi³

2004

Arch Ophthalmol

View full text Add to dashboard Cite

oday, more than ever, ophthalmologists are being asked to answer patients' questions about vitamin supplements and nutrition. The importance of diet and eye health is not new. The need to obtain adequate vitamin A to prevent xerophthalmia and nightblindness, particularly where malnutrition is rampant, has been known for decades (reviewed by Underwood and Arthur 1). More recently, interest has been directed at whether nutritional supplements might prevent loss of vision caused by degenerative conditions that become more common as we age, such as cataract and macular degeneration.

show abstract

Nutritional Factors In Cataract

Cited by 20 publications

References 0 publications

Occurrence of Cataract and Fatty Liver in Captive Plains Viscachas (Lagostomus maximus) in Relation to Diet

Occurrence of Cataract and Fatty Liver in Captive Plains Viscachas (Lagostomus maximus) in Relation to Diet

Vitamin E and risk of age-related cataract: a meta-analysis

Doctor, What Vitamins Should I Take for My Eyes?

Contact Info

Product

Resources

About