Nutritional Considerations in Childhood Acute Lymphoblastic Leukemia

Abstract

The high prevalence of malnutrition in adult

The mosaic puzzle of the therapeutic monoclonal antibodies and antibody fragments - A modular transition from full-length immunoglobulins to antibody mimetics

“…In order to engender the highest cytotoxic effect, the ADCs should be internalized by receptor mediated endocytosis followed by the release of the cytotoxic payload causing the cell death by apoptosis to be induced as a result of the cytoskeletal microtubules and DNA alteration [105] , [106] , [107] . During the last two decades, the FDA approved 14 different ADCs designed for the treatment of a wide spectrum of hematological and non-hematological malignancies[ 108 , 109 ]. Recently, a novel format of the ADCs termed Antibody-Antibiotic Conjugates has been designed to counteract against bacterial infections as a novel modality to limit the emergence of antimicrobial resistance [110] .…”

Phenomenology Study of Nutrition Support in Children with Acute Lymphoblastic Leukemia during Chemotherapy

“…Nutrition is part of the process of life and development of children, so that the fulfillment of nutrition in the process of healing the disease is needed to optimize the success of cancer therapy in children and reduce the risk of ongoing complications. This is in line with Sami's (2020) research which contains nutritional considerations during cancer treatment, including; 1) careful food handling; 2) avoid sugar; 3) focuses on immune-boosting foods; 4) following a restricted diet (a diet dense in nutrition but low in carbohydrates, restrictions on sugar and salt, a diet low in saturated and trans fats); 5) considering other parameters, attention is paid to age, sex, body weight and height to take into account the total energy requirements (Khatib and Omar 2020).…”

“…For solid food, it can be in the form of ordinary food, soft food, or crushed food; 4. If there is difficulty chewing or swallowing, drinking using a straw, food or drink is given at room temperature or cold, the form of food is filtered or liquid, avoid foods that are too acidic or salty (Khatib and Omar 2020). e. Social Economy Friedman (1998) wrote several forms of family support, one of which is financial support.…”