Nutritional and Alternative Approaches to Treatment in Space

Kumar, Akash; Goyal, Nandani; Pramanik, Jhilam; Prajapati, Bhupendra G.; Patel, Jayvadan K.

doi:10.1007/978-3-319-50909-9_58-1

Cited by 1 publication

(2 citation statements)

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“…e intricate interplay between gut microbiota composition and anxiety disorders has emerged as a compelling area of investigation, o ering a novel perspective on anxiety management through the use of psychobiotics. A growing body of empirical evidence underscores the intimate connection between alterations in gut microbiota composition and the manifestation of anxiety disorders [32]. One pivotal study demonstrated the bidirectional communication between the gut and the brain, referred to as the gut-brain axis, and how changes in the gut microbiota can modulate behavior and stress responses [33].…”

Section: Gut Microbiota Composition and Anxietymentioning

confidence: 99%

“…A noteworthy study conducted a groundbreaking investigation utilizing rodent models, revealing a signi cant reduction in anxiety-like behaviors following the administration of a speci c psychobiotic strain. is suggests a potential modulatory role of gut microbiota in anxiety regulation [32]. Complementing this, another study delved into the neurobiological underpinnings of psychobiotic e ects, elucidating alterations in the expression of key neurotransmitters implicated in anxiety modulation [38].…”

Section: Experimental and Clinical Studiesmentioning

confidence: 99%

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Gut microbiota and psychobiotics: a novel approach in anxiety management - a comprehensive literature review

Aththanayaka

2024

J. Ment. Health. Behav. Sci.

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The human gut microbiota, a diverse ecosystem of microorganisms residing in the gastrointestinal tract, has garnered increasing attention for its profound in uence on physical and mental health. Within this context, the dynamic interplay between gut microbiota and anxiety has become a focal point of research, giving rise to the exploration of psychobiotics -live microorganisms with mental health bene ts. This literature review consolidates existing knowledge on the intricate relationship between gut microbiota, psychobiotics, and anxiety, emphasizing the bidirectional communication of the gut-brain axis. The review encompasses evidence from human and animal studies, exploring the impact of psychobiotics on anxiety-related processes through modulating neurotransmitter production, immune responses, and in ammatory processes. While experimental studies in animal models show promising results, clinical trials in humans present varied outcomes, underscoring the need for further research to identify speci c strains and mechanisms governing psychobiotic e ects. Challenges in methodological standardization and the dynamic nature of the gut microbiota necessitate interdisciplinary collaboration and advanced research techniques. Despite challenges, the incorporation of psychobiotics into anxiety management strategies holds promise, o ering a complementary approach to traditional treatments. The potential to tailor interventions based on individual responses to speci c strains aligns with the personalized nature of mental health care. This review concludes by highlighting the implications for anxiety management and the need for continued research to optimize the therapeutic potential of psychobiotics in promoting mental well-being.

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Section: Gut Microbiota Composition and Anxietymentioning

confidence: 99%

Section: Experimental and Clinical Studiesmentioning

confidence: 99%