Nutrition impact symptoms and associated outcomes in post-chemoradiotherapy head and neck cancer survivors: a systematic review

Crowder, Sylvia L.; Douglas, Katherine G.; Pepino, Marta Yanina; Sarma, K.V.S.; Arthur, Anna E.

doi:10.1007/s11764-018-0687-7

Cited by 150 publications

(132 citation statements)

References 32 publications

Supporting

Mentioning

117

Contrasting

Unclassified

Order By: Relevance

“…Concurrent chemoradiotherapy is associated with higher rates of toxicity and complications when compared with surgery or radiation alone (74). Some of the treatment toxicities can be longterm and become chronic: swallowing dysfunction, xerostomia, dental problems, taste alterations, and weight loss have a significant impact on patient's quality of life (75,76). In addition to the nutritional support, symptom-management (i.e., analgesia), psycho-oncological counseling, and speech and language rehabilitation therapy will be essential to improve their quality of life.…”

Section: The Role Of the Specialized Dietitianmentioning

confidence: 99%

The Multidisciplinary Team (MDT) Approach and Quality of Care

et al. 2020

View full text Add to dashboard Cite

The core function of a multidisciplinary team (MDT) is to bring together a group of healthcare professionals from different fields in order to determine patients' treatment plan. Most of head and neck cancer (HNC) units are currently led by MDTs that at least include ENT and maxillofacial surgeons, radiation and medical oncologists. HNC often compromise relevant structures of the upper aerodigestive tract involving functions such as speech, swallowing and breathing, among others. The impairment of these functions can significantly impact patients' quality of life and psychosocial status, and highlights the crucial role of specialized nurses, dietitians, psycho-oncologists, social workers, and onco-geriatricians, among others. Hence, these professionals should be integrated in HNC MDTs. In addition, involving translational research teams should also be considered, as it will help reducing the existing gap between basic research and the daily clinical practice. The aim of this comprehensive review is to assess the role of the different supportive disciplines integrated in an MDT and how they help providing a better care to HNC patients during diagnosis, treatment and follow up.

show abstract

Section: The Role Of the Specialized Dietitianmentioning

confidence: 99%

The Multidisciplinary Team (MDT) Approach and Quality of Care

et al. 2020

View full text Add to dashboard Cite

show abstract

“…This can lead to behavioural changes including avoidance of certain foods, for example dry, spicy or crunchy food, and/or preference for soft and carbohydrate‐rich foodstuff. In turn, changes in food intake can result in nutritional deficiencies, weight loss, malabsorption and atrophy of the masticatory muscles and impaired masticatory performance (Crowder, Douglas, Yanina Pepino, Sarma, & Arthur, ; Dusek et al., ; Gilbert, Heft, & Duncan, ; Jensen et al., ; Loesche et al., ; Pedersen et al., ; Yoshikawa et al., ), leading to further aggravation of the oral health (Sheetal, Hiremath, Patil, Sajjansetty, & Kumar, ). Consequently, salivary gland hypofunction and its associated symptoms and clinical consequences often have a significant negative impact on the patient's social functioning and well‐being and quality of life (Enoki et al., ; Fox et al., ; Gerdin, Einarson, Jonsson, Aronsson, & Johansson, ; Pedersen, Reibel, & Nauntofte, ; Pedersen et al., ; Thomson, Lawrence, Broadbent, & Poulton, ).…”

Section: Introductionmentioning

confidence: 99%

Salivary functions in mastication, taste and textural perception, swallowing and initial digestion

et al. 2018

View full text Add to dashboard Cite

Saliva exerts multiple functions in relation to the initial digestive processes taking place in the upper parts of the gastrointestinal tract. Ingestion of food and beverages, in turn, is a strong stimulus for secretion of saliva with a differential composition depending on the neuronal stimulation pattern. This review paper provides insight into the mechanisms by which saliva acts in relation to taste, mastication, bolus formation, enzymatic digestion and swallowing. Also, the protective functions of saliva including maintenance of dental and mucosal integrity will be discussed as they indirectly influence the digestive process. The final part of this study focuses on the implications of xerostomia and salivary gland dysfunction on gastrointestinal functions.

show abstract

“…irradiation) or systemic (e. g. chemotherapy, EGFR-inhibitors). The symptom describes the inflammation of the enoral mucosa and is -if induced by radiotherapy-often associated with xerostomia, dysgeusia or dental problems (Rubenstein et al 2004; Barrach et al 2015;Kato et al 2017;Crowder et al 2018). Patients may present with erythematous or atrophic lesions of the oral mucosa and in more severe cases with ulcers.…”

Section: Introductionmentioning

confidence: 99%

How to bridge the gap? European medical plants used for treating oral mucositis: on the search for evidence

Buentzel

Bauer

Buentzel

2020

J Cancer Res Clin Oncol

View full text Add to dashboard Cite

Purpose Oral mucositis is a common, painful side effect of cancer treatment-be it locoregional (e.g. irradiation) or systemic (e. g. chemotherapy). Phytotherapy is often used by patients to alleviate symptoms. However, knowledge on which medical plants are recommended by literature about Traditional European Medicine (TEM), their effect(s) on symptoms and their efficacy is severely lacking. Therefore, we developed a novel approach to assess traditional knowledge of herbals used in TEM and searched the online databases for studies reporting effects of these plants. Methods At first, online research did not yield a satisfying number of studies (MESH terms: "mucositis" OR "stomatitis" AND "herbal" OR "herbal medicine"). Trials were labelled by the country conducting the study. In parallel, we compiled a list of 78 plants recommended for treating oral mucositis by screening 14 books on TEM. Then, a "hit list" of the plants most often mentioned was composed and used further for a second online investigation using the Latin plant designations as MESH term. Studies of both online searches were pooled for analysis. Results There is a gap between traditional knowledge and trials investigating medical plants used by TEM. Overall, herbal remedies alleviate oral mucositis and especially, gingivitis well. There is good evidence for using Matricaria recutita L., Salvia officinalis L., Calendula officinalis L. and Thymus spp. L. for treating oral mucositis. Conclusion Clinical trials investigating medical plants known in TEM are rare. However, following our research strategy, we could extrapolate four plants with good evidence for alleviating symptoms of oral mucositis and gingivitis.

show abstract

Nutrition impact symptoms and associated outcomes in post-chemoradiotherapy head and neck cancer survivors: a systematic review

Abstract: The prevalence and consequences of nutrition impact symptoms are substantial among head and neck cancer survivors beyond the acute phase of cancer treatment. Oncology clinicians should continuously monitor and manage these symptoms throughout the cancer continuum.

Cited by 150 publications

References 32 publications

The Multidisciplinary Team (MDT) Approach and Quality of Care

The Multidisciplinary Team (MDT) Approach and Quality of Care

Salivary functions in mastication, taste and textural perception, swallowing and initial digestion

How to bridge the gap? European medical plants used for treating oral mucositis: on the search for evidence

Contact Info

Product

Resources

About