Nutrition and exercise interventions could ameliorate age-related cognitive decline: a meta-analysis of randomized controlled trials

Liu, Ting; Li, Na; Hou, Zongjie; Liu, Linsheng; Gao, Li; Wang, Lin; Tan, Jiying

doi:10.1007/s40520-020-01730-w

Cited by 15 publications

(14 citation statements)

References 49 publications

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“…Tan et al [37] Case-control study (pilot randomized controlled evaluation) 113 Older adults who were engaging in volunteering showed an increase in their physical activity level Sofi et al [30] Systematic meta-analysis of prospective studies 33,816 Physical activity of all levels showed a protective effect on the occurrence of cognitive decline ATTICA study; Kollia et al [27] Observational population study 853 Higher Healthy Aging Index (which included physical activity) was associated with lower 10-year CVD risk Lindsay-Smith et al [35] Observational population study 28 Group-based social and physical activities programs for older people may improve their well-being and prevent loneliness Xu et al [29] Observational population study 613 Physical activity was associated with a reduced risk of developing metabolic syndrome in the participants with the highest levels of physical activity de Oliveira et al [32] Observational population study 200 There was a correlation between low levels of physical activity and symptoms of anxiety and depression in older people Steltenpohl et al [34] Observational population study 39 Older adults were more likely to prefer to exercise with others, rather than alone Liu et al [31] Meta-analysis of randomized controlled trials 1039 In the elderly with cognitive decline, exercise and nutrition interventions showed a positive effect on global cognitive function Barnes et al [33] Observational population study 6994 Loneliness and social isolation in older people was associated with lower quality of life and higher medical costs picking up physical activity later in life has similar, but smaller benefits for health. Almeida et al conducted a study with 10-13 year follow-up, involving 12,201 older men living in Perth, Australia.…”

Section: Resultsmentioning

confidence: 99%

“…Findings of this meta-analysis suggest a strong protective effect of all levels of physical activity against cognitive decline in nondemented adults. Analyzing six randomized controlled trials, Liu et al also found that nutrition combined exercise interventions can have a positive effect on global cognitive function in the elderly with cognitive decline [ 31 ]. Physical activity has also been shown to improve anxiety and depression in older people, thus improving their quality of life [ 32 ].…”

Section: Possible Mechanismsmentioning

confidence: 99%

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Physical activity as a determinant of successful aging: a narrative review article

Szychowska

Drygas

2021

Aging Clin Exp Res

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Population of older people in many countries is constantly growing, therefore the subject of successful aging has become important and a priority for public health policy-makers. A person who is successfully aging has low risk of chronic disease and disability, high physical function, good mental health and social engagement in older age. Lifestyle factors, such as diet and exercise, have been identified as determinants of successful aging. The aim of this narrative review is to compile the evidence from big cohort studies on the overall health of older people. Their results indicate that regular physical activity increases the chances of successful aging in older people, but only after reaching a sufficient threshold. Physical activity lowers the risk of many chronic diseases and cognitive decline commonly associated with older age, promotes social engagement and improves self-estimated well-being.

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Section: Resultsmentioning

confidence: 99%

Section: Possible Mechanismsmentioning

confidence: 99%

Physical activity as a determinant of successful aging: a narrative review article

Szychowska

Drygas

2021

Aging Clin Exp Res

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“…As per a meta-analysis study, an intervention that combined nutrition with exercise was shown to improve age-related cognitive decline, but not memory, attention and executive function. 16 Another study on the relationship between sedentary behaviors and cognitive function in the older adults without dementia showed that sedentary behaviors, such as TV viewing, were associated with cognitive decline and had a negative relationship with verbal memory. 17 …”

Section: Introductionmentioning

confidence: 99%

Effects of Changes in Physical Activity with Cognitive Decline in Korean Home-Dwelling Older Adults

Song¹,

Park²

2022

JMDH

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Purpose The rapidly increasing older adults’ population of South Korea has increased the socioeconomic burden on society due to cognitive decline. In this study, we examined the association between changes in physical activity in the older adults and their cognitive function, a primary criterion for the diagnosis of dementia, using panel data from the 2012–2018 Korean Longitudinal Study of Aging. Patients and Methods This study used baseline (2012) and biennial assessment of follow-up data (2014, 2016, 2018) from Korean Longitudinal Study of Aging. A total of 1733 older adults with the Korean version of the Mini Mental State Examination (K-MMSE) scores in the normal range at the time of the first investigation were included in the study. Physical activity was classified into three categories: inactivity, low physical activity, and high physical activity. Changes in physical activity from 2012 were classified into five groups: remained active, became active in 2016, became active in 2014, became inactive, and remained inactive. Participants’ general and health-related characteristics were used as control variables. Descriptive statistics, chi-square tests, and logistic regression analysis were used for analysis. Results The baseline mean age of the older adults in 2012 was 71.63 years; of the total 1733 participants, 57.1% were inactive, 5.7% had low physical activity, and 37.3% had high physical activity. Changes in physical activity were significantly associated with cognitive decline. Compared to the group that continued regular physical activity, the risk of cognitive decline increased in the case of participants who became or remained inactive. Conclusion Results highlighted the importance of continuous physical activity and its relation to cognitive function. Encouraging continuous physical activity in the older adults has a positive effect on the prevention of cognitive impairment and dementia. Thus, exercise-based interventions should be implemented a community health service.

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“…Age-related cognitive decline (ARCD) is a progressive neurodegenerative disease that is more prevalent in oldest-old adults than in younger adults ( Kioussis et al, 2021 ; Liu et al, 2021 ). According to data from the WHO in 2017, approximately 100 million people have ARCD, and this number will further increase with the increased growth of global aging ( Carman et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

Relationships Between Traditional Chinese Medicine Constitution and Age-Related Cognitive Decline in Chinese Centenarians

Sun

Ping

et al. 2022

Front. Aging Neurosci.

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BackgroundAge-related cognitive decline (ARCD) is a common condition among older adults, affecting 100 million people worldwide. Traditional Chinese Medicine’s (TCM) constitution is closely related to the occurrence and development of diseases in the elderly population. However, little is known about the relationships between TCM constitution and ARCD in the super-aged population. The present study aimed to investigate the relationships between the TCM constitution and ARCD in Chinese centenarians and to explore the application of the constitution to prevent ARCD in the elderly population.MethodsEach participant underwent a standardized epidemiological investigation and physical examination, based on the China Hainan Centenarian Cohort Study. Data on the demographic characteristics and TCM constitution were collected using structured questionnaires.ResultsThe present study included 636 centenarians aged 100–116 years. The prevalence of ARCD was 87.7% (n = 558 centenarians). In multiple linear regression analysis, an inverse relationship between Qi depression and Mini-Mental State Examination scales was significant after controlling for a wide range of other factors (P < 0.05). In multiple logistic regression analysis, Qi depression was positively associated with ARCD after full adjustment (P < 0.05).ConclusionAs the first study in the world, the present study provides strong epidemiological evidence that Qi depression has a significant relationship with ARCD in Chinese centenarians, and regulating Qi depression may be a valuable method to prevent and treat ARCD in the elderly population.

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Nutrition and exercise interventions could ameliorate age-related cognitive decline: a meta-analysis of randomized controlled trials

Cited by 15 publications

References 49 publications

Physical activity as a determinant of successful aging: a narrative review article

Physical activity as a determinant of successful aging: a narrative review article

Effects of Changes in Physical Activity with Cognitive Decline in Korean Home-Dwelling Older Adults

Relationships Between Traditional Chinese Medicine Constitution and Age-Related Cognitive Decline in Chinese Centenarians

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