Nutrigonometry I: Using Right-Angle Triangles to Quantify Nutritional Trade-Offs in Performance Landscapes

Morimoto, Juliano; Conceição, Pedro; Mirth, Christen K.; Lihoreau, Mathieu

doi:10.1086/723599

Cited by 4 publications

(8 citation statements)

References 60 publications

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“…

10^{- 6}

0.002

0.02

and

0.2

) (see Dialog S1). Sex‐specific optimal PC ratio where compared using the angle

θ

and the hypothenuse obtained using the Nutrigonometry model (Morimoto et al., 2023).

θ

and the hypothenuse were calculated within each study and species and the averages of these estimates per species were used for the analysis of phylogenetic signal as described above.…”

Section: Methodsmentioning

confidence: 99%

“…higher variance) estimates of the posterior distribution of the phylogenetic signal for males. I used the Nutrigonometry model to the reconstructed performance landscapes to compute the optimal PC ratio region in the performance landscapes that maximised lifespan in each species (Morimoto et al, 2022(Morimoto et al, , 2023Morimoto & Lihoreau, 2019) (see Section 1 for details).…”

mentioning

confidence: 99%

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Optimum ratio of dietary protein and carbohydrate that maximises lifespan is shared among related insect species

Morimoto

2023

Aging Cell

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Animals often regulate the intake and quantity of nutrients to maximise fitness through life‐history traits such as lifespan, but we still lack a proper understanding of how specific nutrients influence these traits. Here, I developed an algorithm which allowed me to create a nutrient‐specific database from literature data, and investigated how the requirements of protein (P) and carbohydrate (C) needed to maximise lifespan evolved across nine insect species. I found moderate evidence of a phylogenetic signal on the optimal ratio of protein to carbohydrate ratio (PC ratio) that maximised lifespan, suggesting that optimal PC ratio for lifespan could have evolved non‐independently among related species. I also found evidence for weak‐to‐strong sex‐specific optimal PC ratios for lifespan, suggesting that sex‐specific nutritional needs to maximise lifespan can emerge and persist in some species. Although limited in the number of species, the approach adopted here is portable to experiments with number of nutrients and, thus, can be used in complex comparative precision nutrition studies for insights into the evolution of animal nutrition.

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“…

10^{- 6}

0.002

0.02

and

0.2

) (see Dialog S1). Sex‐specific optimal PC ratio where compared using the angle

θ

and the hypothenuse obtained using the Nutrigonometry model (Morimoto et al., 2023).

θ

and the hypothenuse were calculated within each study and species and the averages of these estimates per species were used for the analysis of phylogenetic signal as described above.…”

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Optimum ratio of dietary protein and carbohydrate that maximises lifespan is shared among related insect species

Morimoto

2023

Aging Cell

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“…We used the newly developed ‘Nutrigonometry’ model to test for nutritional trade-offs emerging as a result of fluctuating thermal regimes across the trait response surfaces (Morimoto et al ., 2023). Briefly, Nutrigonometry uses triangulation to identify the peak (or valley) regions of the trait response surfaces, from which comparisons can be made by applying Pythagoras theorem (Morimoto et al ., 2023). Two metrics are calculated using Nutrigonometry: (a) the angle θ i,j , which is an estimate of the distance between the identified location of peak regions in two response surfaces for traits i and j .…”

Section: Methodsmentioning

confidence: 99%

“…The metric h i,j therefore is a proxy for nutritional trade-offs with respect to nutrient intake or quantity (details in Morimoto et al ., 2023). We used Nutrigonometry with a general linear model specification as it was shown to lead to the most accurate identification of peak regions in trait response surfaces (Morimoto et al ., 2023). We estimated the peak region as the region comprising the highest 90% values for the trait response and these regions are represented as red polygons in our trait response surfaces.…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Fluctuating temperatures exacerbate the effects of nutritional stress during development inDrosophila melanogaster

Zanco,

Morimoto,

Cockerell

et al. 2023

Preprint

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Recent studies suggest that elevated temperatures interact with nutrition to exacerbate the negative effects of poor nutrition. Furthermore, populations adapted to distinct environments differ in their sensitivity to combined thermal and nutritional stress. However, most studies have tested these effects using constant temperatures, even though animals in the wild experience daily and seasonal thermal fluctuations. Here, we used two locally-adapted populations ofD. melanogasterfrom the east coast of Australia (a tropical and a temperate population) to ask whether temperature fluctuations interact with nutrition in the same manner as constant temperature conditions to shape life history traits, and how this differs across populations. We found that fluctuating temperatures exacerbate the negative effects of a poor diet when compared to constant temperatures. Moreover, the negative effects of nutritional stress were significantly greater in the tropical population. In contrast, we found that the temperate population was able to utilize nutrition in unique ways to maintain optimal viability under warmer temperatures. Our findings reveal the ways in which temperature and nutrition interact to impact key life history traits in geographically distinct populations, while also highlighting the importance of using temperature assays representative of natural diel cycles when examining insect responses to climate change.

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