Nutraceuticals: Facts and fiction

Espı́n, Juan Carlos; Garcı́a-Conesa, María Teresa; Tomás-Barberán, Francisco A.

doi:10.1016/j.phytochem.2007.09.014

Cited by 697 publications

(413 citation statements)

References 207 publications

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“…Anthocyanins are the major water-soluble flavonoids in blueberries, giving the red, purple and blue color to many fruits and vegetables (Espín et al, 2007). Additionally they are considered biologically active compounds exhibiting a wide range of health benefits, e.g., antioxidant (Cao et al, 1997), antifungal (Benkeblia, 2004), and anti-carcinogenic properties (Ames, 1983).…”

Section: Introductionmentioning

confidence: 99%

Enhanced Antioxidant Capacity of Fresh Blueberries by Pulsed Light Treatment

Rock¹,

Guner²,

Yang³

et al. 2015

JFR

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As a novel technology for food safety risk mitigation, pulsed light (PL) has been shown effective in surface decontamination of fresh blueberries in literature. However, little is known about the effects of PL on the antioxidant capacity and quality characteristics of fresh blueberries. Fresh blueberries from a local farm were treated with PL for 30, 60, 90 and 120 s. Results show that PL exposure enhanced the antioxidant activity (ORAC) and total phenolic content of fresh blueberries 50 and 48% respectively, relative to the control. Pulsed light also significantly increased the total anthocyanin contents, which may be due to the upregulation of Phenylalanine Ammonium Lyase (PAL) enzymes. There was no significant difference (P ≤ 0.05) in the soluble solids, pH, titratable acidity, firmness, color and mass of the fresh blueberries within 120 s PL exposure. In conclusion, PL illumination enhanced the antioxidant capacity of fresh blueberries while maintaining other quality characteristics.

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Section: Introductionmentioning

confidence: 99%

Enhanced Antioxidant Capacity of Fresh Blueberries by Pulsed Light Treatment

Rock¹,

Guner²,

Yang³

et al. 2015

JFR

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“…A large body of evidence, mainly derived from preclinical studies in animals, has concluded that dietary polyphenols, when given in large quantities, can have desirable outcomes [6]. There is currently an extensive range of flavonoid supplements on the market [7]. Suppliers of such supplements recommend daily flavonoid intakes in amounts that are many times higher than those doses which can normally be achieved from a flavonoid-rich diet.…”

Section: Introductionmentioning

confidence: 99%

Effects of Long-Term Use of Flavonoids on the Absorption and Tissue Distribution of Orally Administered Doses of Trace Elements in Rats

Jaccob¹,

Hussain²

2012

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The risk of pharmacokinetic polyphenols-trace elements interaction may undesirable therapeutic outcomes. We evaluate the long-term use of silibinin, epigallocatechin (ECGC), quercetin and rutin on the absorption and tissue distribution of zinc, copper and iron after single oral doses in rats. Five groups of rats received either with olive oil as control or one of the polyphenols silibinin, EPGC, quercetin or rutin, administered orally as oily solutions for 30 days. At day 30, a solution contains sulphate salt of zinc, copper and iron was administered orally; 3 hrs later blood samples, tissues of brain, kidney and liver were obtained for evaluation of the elements levels. The results showed that the polyphenols increased both serum and tissue levels of these elements compared with controls. This effect was relatively varied according to the structural differences among flavonoids. In conclusion, long-term use of supraphysiological doses of flavonoids increase absorption of Zn, Cu and Fe and their tissue availability in brain, kidney and liver; this effect seems to be different with variations in structural features.

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“…Therefore, opportunities abound in functional foods to combat oxidative stress, hyperglycemia, and hypercholesterolemia. Now it's the responsibility of the nutritionists to pay attention towards their health claims and their safety issues [3][4].…”

Section: Introductionmentioning

confidence: 99%

Supplementation of Powdered Black Cumin (Nigella sativa) Seeds Reduces the Risk of Hypercholesterolemia

Sultan

Butt

Ahmad³

et al. 2011

FFHD

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ABSTRACT:Background: Functional and nutraceutical foods are gaining immense popularity among the masses. Plants and their bioactive molecules are of prime importance. Although various plants from different geographical areas have been tested in the past, many horizons still need to be addressed. Black cumin (Nigella sativa L.) is one such example that is quite popular in South Asia and the Middle East.

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Nutraceuticals: Facts and fiction

Cited by 697 publications

References 207 publications

Enhanced Antioxidant Capacity of Fresh Blueberries by Pulsed Light Treatment

Enhanced Antioxidant Capacity of Fresh Blueberries by Pulsed Light Treatment

Effects of Long-Term Use of Flavonoids on the Absorption and Tissue Distribution of Orally Administered Doses of Trace Elements in Rats

Supplementation of Powdered Black Cumin (Nigella sativa) Seeds Reduces the Risk of Hypercholesterolemia

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