Nutmeg nutraceutical constituents: In vitro and in vivo pharmacological potential

Abstract

Spices consumptions are in direct relation with the healthy survivability of consumers throughout life as they are loaded with lists of phytoconstituents of human values.Nutmeg owes to its essential, volatile, and fixed oil is in prime most interest by researchers to explore for its benefits through food utilization. Besides being loaded with these phytochemical-based benefit traits it is also rich on the mineral side preferably with potassium, magnesium, and phosphorous. As for as the oil variation is concern, nutmeg essential oil composition behaves as per the geographical and varietal factors. Its beneficial aspect highlighted wherein oil of nutmeg contains Myristicin (phenylpropene organic compound) can exhibit anti-inflammatory response and have the cytotoxic activity against human colorectal carcinoma (HCT-116) and human breast carcinoma Michigan Cancer Foundation (MCF-7). Associated benefits of being on antiangiogenic compounds such as myristicin in Myristica fragrans essential oil resulted in antiangiogenic activity with an IC 50 of 77.64 g/ml. Practical applicationsNutmeg has its wider acceptability among medicinal and therapeutic uses in today's world. Indeed, many would say that nutmeg use has increased. Nutmeg's traditional applications in treating stomach conditions, curing rheumatic pain, soothing skin wounds and illnesses, and acting as a relaxing agent have resulted in extensive research into its various extracts and fractions. One of the most commonly observed habits is the influence of nutmeg essential oil and extracts on the central nervous system. Nutmeg acetone extract's antioxidant and antimicrobial properties can help to prevent or delay oxidative stress-related diseases and infections caused by opportunistic pathogenic microorganisms. Nutmeg requires further work on several fronts, including the advancement of analytical approaches, reproducible separation procedures, and successful synthetic methods for promising secondary metabolites, as a source of complex secondary metabolites with substantial potential as prototype agents for drug testing.

Effect of Sustainable Pretreatments on the Nutritional and Functionality of Chickpea Protein: Implication for Innovative Food Product Development

“…Dehulling and splitting can be achieved through two methods: dry milling and wet milling [81]. Te process of milling or grinding chickpeas leads to the release of a slightly nutty and four-like odor [82]. Tis mechanical breakdown of the chickpea structure results in a more concentrated, nutty, and mildly savory favor compared to whole chickpeas.…”

Unique biomedical application of fluorescence derivatization based on palladium‐catalyzed coupling reactions for HPLC analysis of pharmaceuticals and biomolecules

“…Myristicin may sometimes be abused by consuming large amounts of it, which results in hallucinations. Myristicin may have serious negative health consequences in these situations, such as palpitations, delirium and convulsions (Malik et al, 2021). Therefore, a sensitive technique for analysis, like FL determination, was very much needed.…”

PEMANFAATAN POTENSI ALAM KOTA REMPAH MELALUI PENGOLAHAN MINYAK ATSIRI DAGING BUAH PALA (Myristica fragrans) DI KELURAHAN TANAH TINGGI BARAT KOTA TERNATE

“…Pembuatan Minyak Atsiri Daging Buah Pala Minyak atsiri (EO) menunjukkan sifat antioksidan dan antimikroba (Keawchai et al, 2021). Manfaat terkait senyawa antiangiogenik seperti miristisin pada minyak atsiri Myristica fragrans menghasilkan aktivitas antiangiogenik dengan IC50 sebesar 77,64 g/ml (Malik et al, 2022). Daging buah dan daun pala memiliki aktivitas antimikroba terhadap bakteri Escherichia coli, Staphylococcus aureus, Propionibacterium acne dan jamur Candida albicans dengan diameter hambat yang bervariasi (Nasir & Marwati, 2022).…”