Nurse-administered propofol–alfentanil sedation using a patient-controlled analgesia pump compared with opioid–benzodiazepine sedation for outpatient colonoscopy

Abstract

Despite higher costs, nurse-administered propofol-alfentanil sedation using a PCA pump can provide deeper conscious sedation, comparable satisfaction, and similar complication risks compared with conventional opioid-benzodiazepine sedation.

Prospective Evaluation of the Routine Use of a Nasopharyngeal Airway (Wendl Tube) during Endoscopic Propofol-Based Sedation

“…In GI endoscopy, sedation has been increasingly adopted as a routine procedure by most endoscopists for improving patient tolerance and relieving patient anxiety [11]. The use of the sedative propofol has significantly increased over the past years due to its pharmacological benefits with rapid onset and short duration of action [12] resulting in rapid patient recovery upon completion of the procedure [13,14].…”

Low effect‐site concentration of propofol target‐controlled infusion reduces the risk of hypotension during endoscopy in a Taiwanese population

“…Several methods have been utilized in the prescription of propofol including the continuous infusion method, nurse‐administered propofol sedation, patient‐controlled and computer‐controlled sedation …”

“…5,15 Several methods have been utilized in the prescription of propofol including the continuous infusion method, nurse-administered propofol sedation, patient-controlled and computer-controlled sedation. [17][18][19] TCI method allows i.v. administration of propofol using an infusion pump.…”

Patient-controlled sedation with propofol and remifentanil for ERCP: a randomized, controlled study

“…Other studies have shown that PCS can be used with nurse surveillance safely and effectively for colonoscopy. 3,22 Given the observed low incidence of adverse event rates, high sedation success rates, and minimal requirements for anesthesiologist intervention among patients who received PCS, we believe that PCS can be provided by a nurse specialist for ERCP as well. Such a nurse would need to be trained to recognize hypoventilation and other sedationrelated complications and be prepared to rescue patients from levels of sedation deeper than intended.…”

“…[1][2][3][4][5][6][7][8][9] Propofol sedation is associated with rapid onset of action, fast recovery, good patient cooperation, and a high satisfaction level, as judged by both patients and endoscopists. Sedation is usually induced with a bolus of propofol and thereafter maintained with a constant infusion titrated individually.…”