Nummular headache: another case treated with gabapentin

Trucco, Marco

doi:10.1007/s10194-007-0375-x

Cited by 31 publications

(33 citation statements)

References 3 publications

(2 reference statements)

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“…The intensity of pain was severe, which was similar to the cases already reported (3,4,8,13,14,19,25,26), although it is worth noting that NH pain is typically described as mild to moderate (18,23). The majority of the pain quality of NH has been described as pressing, burning or dull (8,11,19,23,24,26,29,32). Lancinating pain attacks, without baseline pain, as the only manifestation (2 patients) have only previously been reported by Ruscheweyh et al (27); the present case brings this total to three.…”

Section: Discussionsupporting

confidence: 82%

A new variant nummular headache: large diameter accompanied with bitrigeminal hyperalgesia and successful treatment with carbamazepine

Man

Yu²,

Li³

et al. 2010

Turkish Neurosurgery

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Nummular headache (NH) is defined as a focal head pain that is exclusively felt in a small area, which is typically 1-6 cm in diameter. Neurological examinations are normal in all patients, but this report describes a new variant. A patient was identified who presented with focal head pain that was approximately 8 cm in diameter and bitrigeminal hyperalgesia on neurological examination. Treatment with carbamazepine provided significant analgesic relief in terms of both the frequency and intensity of pain. The findings enlarge the clinical diversity of this headache disorder. The pathogenic mechanisms of NH may be similar to trigeminal neuralgia in particular patients.

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Section: Discussionsupporting

confidence: 82%

A new variant nummular headache: large diameter accompanied with bitrigeminal hyperalgesia and successful treatment with carbamazepine

Man

Yu²,

Li³

et al. 2010

Turkish Neurosurgery

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show abstract

“…Patients rarely experience any accompanying symptoms, and there have not been any precipitating factors identified in studies to date . Studies thus far have identified response among patients to treatment with NSAIDS – including indomethacin7‐9 – as well as with gabapentin,6,10‐12 botulinum toxin, carbamazepine, tricyclic antidepressants, and neurotropin . Recent studies utilizing transcutaneous electrical nerve stimulation have also been reported to be effective .…”

Section: Discussionmentioning

confidence: 99%

Can Temporal Course of Pain Determine Patient Response to Specific Medication in Nummular Headache?

Kurian

Solomon

2014

Headache

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“…Spontaneous or triggered exacerbation lasting from seconds to days may superimpose on the background pain . Local sensory dysfunction was frequently reported even in the symptom‐free period . Additionally, 3.8% (12/312) of patients reported focal tropic changes, including skin depression, hair loss, red discoloration, increased temperature and heterochromatic changes within the painful areas (Table ).…”

Section: Literature Reviewmentioning

confidence: 97%

“…Autoimmune disorders or structural lesions of the cranium, pituitary, or vasculature have been reported previously . Overly, 32% of patients had a history of brain trauma or surgery before NH development . Insect bites and varicella‐zoster virus infection were reported in individuals …”

Section: Literature Reviewmentioning

confidence: 99%

Nummular Headache: 2 Cases With Good Beta Blocker Responses and a Narrative Review

Jiang

Liu

et al. 2019

Headache

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Objective To report 2 new nummular headache (NH) cases and review the clinical features and management of NH. Background NH is a coin‐shaped headache with a fixed shape and size. Since the first case series was reported by Pareja, approximately 300 cases have been reported. However, the latest treatment status and pathogenesis of NH remain unclear. Methods Two new NH cases with improved symptomatic responses to metoprolol were reported. We also conducted a narrative review of cases published in English aiming to provide the newest information about the clinical features and management of NH. Results Two NH patients with skin depressions within the painful area experienced significantly improvement with metoprolol. The literature review showed that NH was mainly moderate‐to‐severe in 77.8% (186/239) of the patients. Sensory dysfunction and focal trophic changes were reported in 47.8% (149/312) and 3.8% (12/312) of the patients, respectively. Gabapentin was the most commonly used and effective prophylactic, with a responder rate of 67.9% (55/81). Botulinum toxin type A was used for refractory NH, with an effective rate of 81.8% (9/11). Ten patients from the previous studies were prescribed β‐adrenergic blockers without any relief, and none of them reported focal tropic changes. Conclusions NH can be a disabling headache in more than half of identified patients and requires medical intervention. As with the previous treatment recommendations, gabapentin was the most commonly used prophylactic with a good response. Our cases suggested that β‐adrenergic blockers could be a therapeutic option for NH patients with focal trophic changes within the areas.

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Nummular headache: another case treated with gabapentin

Cited by 31 publications

References 3 publications

A new variant nummular headache: large diameter accompanied with bitrigeminal hyperalgesia and successful treatment with carbamazepine

A new variant nummular headache: large diameter accompanied with bitrigeminal hyperalgesia and successful treatment with carbamazepine

Can Temporal Course of Pain Determine Patient Response to Specific Medication in Nummular Headache?

Nummular Headache: 2 Cases With Good Beta Blocker Responses and a Narrative Review

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