Numerical study of non-Fourier thermal ablation of benign thyroid tumor by focused ultrasound (FU)

Namakshenas, Pouya; Mojra, Afsaneh

doi:10.1016/j.bbe.2019.05.003

Cited by 20 publications

(6 citation statements)

References 33 publications

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“…That is, when the sensitivity of the two diagnostic techniques is high, the diagnostic sensitivity of SMI technology is slightly higher than that of contrast-enhanced ultrasound, and the diagnostic specificity of contrast-enhanced ultrasound is slightly higher than that of SMI. This result shows that SMI technology and contrast-enhanced ultrasound examination have certain diagnostic efficiency and application value for the diagnosis of benign and malignant thyroid nodules, but the diagnostic efficiency and application value of SMI technology is slightly higher than that of contrast-enhanced ultrasound examination [ 21 – 24 ].…”

Section: Diagnosis Test Of Thyroid Benign and Malignant Nodulesmentioning

confidence: 99%

[Retracted] The Application Value of SMI Technology and Contrast‐Enhanced Ultrasound in the Differential Diagnosis of Benign and Malignant Thyroid Nodules

Tian

Sun

et al. 2022

Contrast Media & Molecular Imaging

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Thyroid disease has always been a common and frequent disease in clinical medicine, and its disease detection rate has been increasing year by year. Thyroid diseases are mainly divided into two categories: thyroid diseases treated by medical treatment and thyroid diseases treated by surgery. Thyroid cancer has also become one of the most common malignant secretory tumor diseases today. Ultrasound examination is a commonly used method for diagnosing thyroid diseases. During the diagnosis process, doctors need to observe the characteristics of ultrasound images and combine professional knowledge and clinical experience to give the patient’s disease status. With the improvement of people’s living standards and health awareness, thyroid disease has become an important issue that plagues the health of Chinese residents. Therefore, people and medical workers are paying more attention to thyroid disease. In recent years, various ultrasound technologies have been applied in the differential diagnosis of benign and malignant thyroid nodules and have played an important role in the diagnosis. This article aims to study the application value of SMI technology (ultra-microvascular imaging technology) and contrast-enhanced ultrasound in the differential diagnosis of thyroid benign and malignant nodules. It conducts diagnostic experiments and analysis on some cases of benign and malignant thyroid nodules through the use of SMI diagnostic methods and contrast-enhanced ultrasound examination methods. And the ROC curve was used to calculate the sensitivity of SMI technology and ultrasound for the identification and diagnosis of thyroid benign and malignant nodules, and the results were 0.83 and 0.81, respectively. It is concluded that SMI technology and contrast-enhanced ultrasound examination have good diagnostic efficiency and application value for the identification and diagnosis of thyroid benign and malignant nodules.

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Section: Diagnosis Test Of Thyroid Benign and Malignant Nodulesmentioning

confidence: 99%

[Retracted] The Application Value of SMI Technology and Contrast‐Enhanced Ultrasound in the Differential Diagnosis of Benign and Malignant Thyroid Nodules

Tian

Sun

et al. 2022

Contrast Media & Molecular Imaging

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“…Table 1 Thickness of tissue layers and their corresponding acoustic and thermal properties [12,21,22,37,[44][45][46][47][48][49] Table 2 Ultrasound exposure time at 10 W and 15 W.…”

Section: Table Caption Listmentioning

confidence: 99%

“…Kumar et al(2016) reported a Dual Phase Lag (DPL) model for simulating the response of multilayer tissue composed of dermis, subcutaneous, fat, and muscle layers to HIFU [21]. Namakshenas et al (2019) modelled thermal ablation of a thyroid tumor using HIFU [22]. Lin and colleagues (2013) published a study [23] based on the spheroidal beam equation and numerical alternate direction implicit method to assess the influence of ribs on therapeutic ultrasound propagation.…”

Section: Introductionmentioning

confidence: 99%

Pulsed Ultrasound Assisted Thermo-Therapy for Subsurface Tumor Ablation: A Numerical Investigation

Singh

Paul

Shekhar

et al. 2021

Journal of Thermal Science and Engineering Applications

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High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict temperature elevation and corresponding thermal dose distribution in target tissues. We report a parametric numerical study of the thermal response and corresponding of thermal dose in a soft tissue in response to ultrasound. We compared the predictions of tissue models with two, three and seven layers, to ultrasound induced heating at duty cycles ranging from 0.6 and 0.9. Further, two tumor sizes and transducer powers (10 W and 15 W) were considered. Inhomogeneous Helmholtz equation was coupled with Pennes bio-heat equation to predict heating in response to pulsed ultrasound. Necrotic lesion size was calculated using the cumulative equivalent minute (CEM) thermal dose function. In-vitro experiments were performed with agar-based tissue phantoms as a preliminary validation of the numerical results. The simulations conducted with the seven layered model predicted up to 33.5% lower peak pressure amplitude than the three-layered model. As the ultrasound pulse width decreased with the equivalent sonication time fixed, the corresponding magnitude of the peak temperature and the rate of temperature rise decreased. Pulsed ultrasound resulted in increased the volume of necrotic lesions for equivalent time of sonication. The findings of this study highlight the dependence of HIFU-induced heating on target geometry and acoustic properties, and could help guide the choice of suitable ultrasound exposure parameters for further studies.

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“…However, contrary to our study, their model focused on two treatment strategies related to the electrode system, i.e., singlecooled-electrode modality and two-cooled-electrode system. In addition, other studies considered the development of an FE model of the thyroid, but the simulations were focused on a different treatment method, e.g., focused ultrasound [29,30]. Other publications focused on the development of FE models of the neck region for the analysis of bioheat transfer in the human neck and subsequent comparison with images achieved with infrared thermography [25,31,32].…”

Section: Introductionmentioning

confidence: 99%

Model-Optimizing Radiofrequency Parameters of 3D Finite Element Analysis for Ablation of Benign Thyroid Nodules

Bini,

Pica,

Marinozzi

et al. 2023

Bioengineering

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Radiofrequency (RF) ablation represents an efficient strategy to reduce the volume of thyroid nodules. In this study, a finite element model was developed with the aim of optimizing RF parameters, e.g., input power and treatment duration, in order to achieve the target volume reduction rate (VRR) for a thyroid nodule. RF ablation is modelled as a coupled electro-thermal problem wherein the electric field is applied to induce tissue heating. The electric problem is solved with the Laplace equation, the temperature distribution is estimated with the Pennes bioheat equation, and the thermal damage is evaluated using the Arrhenius equation. The optimization model is applied to RF electrode with different active tip lengths in the interval from 5 mm to 40 mm at the 5 mm step. For each case, we also explored the influence of tumour blood perfusion rate on RF ablation outcomes. The model highlights that longer active tips are more efficient as they require lesser power and shorter treatment time to reach the target VRR. Moreover, this condition is characterized by a reduced transversal ablation zone. In addition, a higher blood perfusion increases the heat dispersion, requiring a different combination of RF power and time treatment to achieve the target VRR. The model may contribute to an improvement in patient-specific RF ablation treatment.

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Numerical study of non-Fourier thermal ablation of benign thyroid tumor by focused ultrasound (FU)

Cited by 20 publications

References 33 publications

[Retracted] The Application Value of SMI Technology and Contrast‐Enhanced Ultrasound in the Differential Diagnosis of Benign and Malignant Thyroid Nodules

[Retracted] The Application Value of SMI Technology and Contrast‐Enhanced Ultrasound in the Differential Diagnosis of Benign and Malignant Thyroid Nodules

Pulsed Ultrasound Assisted Thermo-Therapy for Subsurface Tumor Ablation: A Numerical Investigation

Model-Optimizing Radiofrequency Parameters of 3D Finite Element Analysis for Ablation of Benign Thyroid Nodules

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