With the As 2 Se 3 photonic crystal fiber (PCF), the effect of pump power and wavelength on modulation instability (MI) gain is studied in detail. Due to high Raman scattering effect and high nonlinearity of As 2 Se 3 PCF, ultra-broadband MI gain is obtained when appropriate pump power and wavelength is chosen, and the optimal MI gain bandwidth reaches 2812 nm. More importantly, competing between Raman scattering and four-wave mixing results in a single gain peak observed in the anti-Stokes region of As 2 Se 3 PCF when pump power is higher than about 3000 W, while there is no gain spectrum in the fiber Stokes region. The phenomenon is found for the first time, and the obtained single gain peak mainly results from Raman scattering effect.