Numerical modelling of the sticking process of a S. aureus bacterium

Modeling Bacterial Adhesion to Unconditioned Abiotic Surfaces

“…3 Phrased loosely, this model combines xDLVO theory with the Hertzian contact model, while also including an ad hoc snap-in mechanism and energy dissipation. Recently, this model has been extended to mimic flow chamber experiments and determine if a given bacterial strain will adhere to a given surface (Jasevičius and Kruggel-Emden, 2017). Therefore, an initial velocity and viscous drag was included into the model and it was demonstrated that Staphylococcus aureus cells stick to a glass surface.…”

Numerical Modeling of Thrombocyte Interaction Mechanics with a Blood Vessel Wall

“…Newton's second law is applied to describe the movement of a platelet (thrombocyte), Jasevičius et al [11][12][13][14][15].…”

“…In numerical simulations, a platelet can be considered as a particle. Taking into account the model features of the interaction of particles (Jasevičius and Kruggel-Emden [11]; Jasevičius et al [12][13][14][15]) Newton's second law, and the method of discrete elements, the developed model, originally intended for analyzing the motion of microobjects, can be adapted to describe the motion of a biological cell. Applying the established model, this study will allow the description of platelet interactions taking into account the platelet mechanical parameters taken from known physical experiments.…”

“…When describing the deformation of a cell, the Hertz force is applied, which estimates the geometric nonlinearity of the cell, and the stiffness depends on the displacement, Jasevičius et al [11][12][13][14][15]:…”

“…Therefore, subsequent studies focused on the case where the platelet is activated and will have a slightly changed surface geometry as well as changed surface adhesive properties. Further investigation will be concentrated on sticking (Jasevičius and Kruggel-Emden [11]; Feghhi and Sniadecki [38]) of the thrombocyte to a certain surface.…”