“…Recently, a number of S-glycosides, a new non classical class of nucleosides, have been proved to be potential anticancer agents against many cell lines [17][18][19][20][21][22]. Elgemeie et al described the synthesis of series of heterocyclic thioglycosides, pyridine [33], benzisoquinoline [16] and pyrimidinthione [34] thioglycosides and revealed their potential antitumor activities. A novel dihydropyridine -S-glycoside B was identified as strong P-glycoprotein antagonist with significant cytotoxic activity against human colon carcinoma cells [20].…”