Nuclear envelope dynamics in connection to chromatin remodeling

Abstract

SUMMARYThe nucleus is a central organelle of eukaryotic cells undergoing dynamic structural changes during cellular fundamental processes such as proliferation and differentiation. These changes rely on the integration of developmental and stress signals at the nuclear envelope (NE), orchestrating responses at the nucleo‐cytoplasmic interface for efficient genomic functions such as DNA transcription, replication and repair. While in animals, correlation has already been established between NE dynamics and chromatin remodeling using last‐generation tools and cutting‐edge technologies, this topic is just emerging in plants, especially in response to mechanical cues. This review summarizes recent data obtained in this field with more emphasis on the mechanical stress response. It also highlights similarities/differences between animal and plant cells at multiples scales, from the structural organization of the nucleo‐cytoplasmic continuum to the functional impacts of NE dynamics.

Advances in plant chromatin

“…The review of Marie-Edith Chaboute and Alexander Berr's lab (Dupouy et al, 2024) describes how the components of the nuclear envelope sense outside signals and transmit them to the interior of the plant nucleus. An example of this is the sensing of mechanical force, which causes cell wall deformation in plants, being transmitted via microtubules and microfilaments to the nuclear envelope.…”