Novel uric acid-based nano organocatalyst with phosphorous acid tags: Application for synthesis of new biologically-interest pyridines with indole moieties via a cooperative vinylogous anomeric based oxidation

Abstract

In this study, we have designed, synthesized and full characterized a novel biological based acidic nano organocatalyst via condensations reaction of uric acid and phosphorous acid. The obtained compound was named theacrine tetrakis(phosphonic acid) (TTPA) and prepared under refluxing ethanol. This new nano organocatalyst was applied as an efficient and recyclable catalyst for the preparation of novel pyridines with indole moieties via a cooperative vinylogous anomeric based oxidation with good to excellent yields.

Applications of novel composite UiO-66-NH2/Melamine with phosphorous acid tags as a porous and efficient catalyst for the preparation of novel spiro-oxindoles

“…5a–d). The structure and morphology of UiO-66-NH 2 are in agreement with the references, and the structure takes the form of fcu 11–36 (Fig. 5a and b).…”

“…12–14 This method has been introduced for MOFs that are assembled and modified with different chemical reagents while their structures and networks remain stable. 15,16 We have used post-modification method for coupling phosphorus acid tags with MOFs, 17–19 carbon quantum dots 20 and mesoporous materials, 21 as well as melamine, 22 glycoluril 23 and uric acid 24 as novel catalysts. In this study, phosphorus acid tags were incorporated into UiO-66-NH 2 /Melamine, to fabricate the porous and heterogeneous catalyst, UiO-66-NH 2 /Melamine/[N(CH 2 PO 3 H 2 ) 2 ] 2 .…”

Catalytic synthesis of new pyrazolo [3,4-b] pyridine via a cooperative vinylogous anomeric-based oxidation

“…Then, intermediate ( III ) via interaction of lone pair electrons of N atoms from C=C bonds causes the release hydride and H 2 . Finally, the 1,4-dihydropyridines convert to their corresponding pyrazolo [3,4- b ] pyridine derivatives via a CVABO and release a hydrogen molecule (–H 2 ) 80 , 81 . The optimization of model reaction under argon and N 2 atmospheres are also verified the desired product (Fig.…”

Catalytic Application of a Novel Basic Alkane‐sulfonate Metal‐organic Frameworks in the Preparation of Pyrido[2,3‐d]pyrimidines via a Cooperative Vinylogous Anomeric‐based Oxidation

“…[41] Also, this concept for the reduction of compounds by NADH and NADPH 2 has acted via a hydride transfer. [14][15][16][17][42][43][44][45] The development of cooperative vinylogous anomeric-based oxidation (CVABO) is at the forefront of organic chemistry due to the importance of this concept in promoting the synthesis of organic compounds with biological properties. [38][39][40] Recently, we have reviewed the role of the above-mentioned concepts comprehensively.…”