Novel trends and concepts in the nutritional management of glycemia in type 2 diabetes mellitus—beyond dietary patterns: a narrative review

Pafili, Zoe; Dimosthenopoulos, Charilaos

doi:10.1007/s42000-021-00314-1

Cited by 1 publication

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“…Moreover, eating breakfast has benefits for metabolic health and could prevent the onset of T2D in some individuals [ 35 ]. However, some studies suggest that having breakfast as the largest meal of the day is associated with the greatest benefits, while others believe lunch is the better time to eat the largest meal [ 29 , 59 ]. Therefore, reducing dinner may be the best approach to reducing T2D, as a longer overnight fast is more similar to the eating pattern of our ancestors, and earlier eating times seem to reduce T2D risk.…”

Section: The Circadian Clock the Gut Microbiome And Metabolic Hormonesmentioning

confidence: 99%

Can Circadian Eating Pattern Adjustments Reduce Risk or Prevent Development of T2D?

Harris

Czaja

2023

Nutrients

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Type 2 diabetes (T2D) is a chronic condition that occurs in insulin-resistant people with reduced glucose uptake. It is contributed to and exacerbated by a poor diet that results in accumulation of adipose tissue, high blood sugar, and other metabolic issues. Because humans have undergone food scarcity throughout history, our species has adapted a fat reserve genotype. This adaptation is no longer beneficial, as eating at a higher frequency than that of our ancestors has had a significant effect on T2D development. Eating at high frequencies disrupts the circadian clock, the circadian rhythm, and the composition of the gut microbiome, as well as hormone secretion and sensitivity. The current literature suggests an improved diet requires meal consistency, avoiding late-night eating, low meal frequency, and fasting to increase metabolic health. In addition, fasting as a treatment for T2D must be used correctly for beneficial results. Early time-restricted eating (TRE) provides many benefits such as improving insulin resistance, cognitive function, and glycemic control. Alternate-day fasting (ADF), 5:2 fasting, and long-term fasting all have benefits; however, they may be less advantageous than early TRE. Therefore, eating pattern adjustments can be used to reduce T2D if used correctly.

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Section: The Circadian Clock the Gut Microbiome And Metabolic Hormonesmentioning

confidence: 99%

Can Circadian Eating Pattern Adjustments Reduce Risk or Prevent Development of T2D?

Harris

Czaja

2023

Nutrients

View full text Add to dashboard Cite

show abstract

Novel trends and concepts in the nutritional management of glycemia in type 2 diabetes mellitus—beyond dietary patterns: a narrative review

Cited by 1 publication

References 82 publications

Can Circadian Eating Pattern Adjustments Reduce Risk or Prevent Development of T2D?

Can Circadian Eating Pattern Adjustments Reduce Risk or Prevent Development of T2D?

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