“…Some compounds showed notable antibiofilm activity and no bactericidal effect, which can effectively control biofilm formation without affecting the growth of planktonic bacteria, reducing the possibility of bacterial resistance formation (Deng et al., 2022). In addition, synthetic compounds inspired by marine alkaloids have proven to be potent inhibitors of bacterial biofilm (Khadake et al., 2021; Rane et al., 2015). For example, structural modifications of bromotyrosine alkaloids were found to improve their antimicrobial activity (Andjouh & Blache, 2015, 2019).…”