Novel Stereoselective Synthesis of (E)‐Cinnamonitriles via Heck Arylation of Acrylonitrile Catalyzed by a Silica‐Supported Bidentate Arsine Palladium(0) Complex.

Abstract

Nitriles Q 0520 Novel Stereoselective Synthesis of (E)-Cinnamonitriles via Heck Arylation of Acrylonitrile Catalyzed by a Silica-Supported Bidentate Arsine Palladium(0)Complex. -This newly found method is completely (E)-selective, uses a reusable polymer bound catalyst, has simple reaction procedure, easy work-up and gives excellent yields. -(CAI*, M.; TONG, X.; CHEN, J.; HUANG, Y.; J.