Novel repaglinide complexes with manganese(II), iron(III), copper(II) and zinc(II): Spectroscopic, DFT characterization and electrochemical behaviour

“…The binding energy E binding is estimated by the difference between the optimized complex energy (E complex ) and the sum of the isolated metal salt (MCl 2 ) energy (E MCl2 ) and the isolated ligand energy (E ligand ) [66]. The calculation of the binding energies E binding for the synthesized complexes allow to compare the stability of these complexes.…”

Section: Complexes Stabilitymentioning

confidence: 99%

Impact of the functionalized tetrazole ring on the electrochemical behavior and biological activities of novel nickel (II) complexes with a series of tetrazole derivatives

Allab

Chikhi

Zaater

et al. 2020

Inorganica Chimica Acta

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Six new nickel (II) complexes with a series of tetrazole derivatives functionalized by different substituents {5-(2-(1-Benzyltetrazol-5-yl) phenyl)-2-ethyl-4-methylthiazole (L 1), 1-Benzyl-5-(2-(1methylpyrrol-2-yl)phenyl) tetrazole (L 2), 5-(2-(1-Pivalyltetrazol-5-yl)phenyl)-2-ethyl-4methylthiazole (L 3), 5-(2-(1-Methylpyrrol-2-yl) phenyl)-1-pivalyltetrazole (L 4), 2-Ethyl-4-methyl-5-(2-(1 methyltetrazol-5-yl) phenyl) thiazole (L 5) and 1-Methyl-5-(2-(1-methylpyrrol-2-yl)phenyl) tetrazole (L 6)} have been synthesized and characterized by analytical and spectral methods. The data clearly indicated that the nickel (II) complexes are coordinated to the monodentate tetrazole derivatives via nitrogen (N3) atom of the tetrazole ring. The octahedral geometry is observed for all the complexes. The thermogravimetric analysis revealed the presence of coordinated and hydrated water molecules in the coordination sphere. The DFT calculations performed on both the ligands and the complexes allowed to optimize the structures, the stability and to explain the electrochemical behavior and the biological activities of the nickel (II) complexes. The study of the substituents effects on the redox properties of the ligands and their nickel (II) complexes were discussed via cyclic voltammograms. Electron donating substituents shift the reduction potentials toward negative values, while anodic shift of the oxidation potentials is manifested by the substituents having an electron withdrawing effect. The in vitro antimicrobial activities of the ligands and their corresponding nickel (II) complexes have been evaluated against four bacterial and two fungal strains.

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“…The copper(II) ion, paramagnetic d 9 configuration, enables the generated strong metal–ligand (M–L) bonding through hard–soft acid–base (HSAB) principles [ 8 ]. Many copper(II) coordination complex geometry with different coordination numbers have been reported, such as distorted tetrahedral or square planar [ 9 ], tetragonal bipyramidal [ 10 ], square pyramidal [ 11 ] and distorted octahedral [ 12 ] according to a typical Jahn–Teller effect [ 13 ]. The Jahn–Teller effect strongly results in the electron distribution that affects the arrangement of atoms in crystal structure.…”

Section: Introductionmentioning

confidence: 99%

A Single Crystal Hybrid Ligand Framework of Copper(II) with Stable Intrinsic Blue-Light Luminescence in Aqueous Solution

et al. 2021

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Single-crystal solid–liquid dual-phase hybrid organic–inorganic ligand frameworks with reversible sensing response facilitated by external stimuli have received significant attention in recent years. This report presents a significant leap in designing electronic structures that display reversible dual-phase photoluminescence properties from single-crystal hybrid ligand frameworks. Three-dimensional Cu(C3N2H4)4Cl2 complex frameworks were formed through the intermolecular hydrogen bonding and π⋯π stacking supramolecular interactions. The absorption band peaks at 627 nm were assigned to d–d transition showing 10Dq = 15,949 cm−1 and crystal field stabilization energy (CFSE) = 0.6 × 10Dq = 114.4 kJmol−1, while the ligand-to-metal charge transfer (LMCT) of complexes was displayed at 292 nm. The intense luminescence band results from LMCT present at 397 nm. Considering its structure, air stability, framework forming and stable luminescence in aqueous solution, the Cu(C3N2H4)4Cl2 complex shows potential for luminescence Cu-based sensors using emission intensity to detect heavy metal ion species.

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Novel repaglinide complexes with manganese(II), iron(III), copper(II) and zinc(II): Spectroscopic, DFT characterization and electrochemical behaviour

Cited by 10 publications

References 28 publications

New complexes of manganese (II) and copper (II) derived from the two new furopyran-3, 4-dione ligands: Synthesis, spectral characterization, ESR, DFT studies and evaluation of antimicrobial activity

New complexes of manganese (II) and copper (II) derived from the two new furopyran-3, 4-dione ligands: Synthesis, spectral characterization, ESR, DFT studies and evaluation of antimicrobial activity

Impact of the functionalized tetrazole ring on the electrochemical behavior and biological activities of novel nickel (II) complexes with a series of tetrazole derivatives

A Single Crystal Hybrid Ligand Framework of Copper(II) with Stable Intrinsic Blue-Light Luminescence in Aqueous Solution

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