Novel polymeric film coatings for colon targeting: How to adjust desired membrane properties

Pectin grafted poly(N‐vinylpyrrolidone): Optimization and in vitro controllable theophylline drug release

“…The different hydrogel formulations prepared in this work were investigated for in vitro theophylline release. Enteric‐coated dosage forms are often used in colon‐targeted drug delivery to avoid variations in gastric emptying 29. Therefore, dissolution studies were conducted at pH 5.5 and pH 7.4 representing that of small intestines and colon respectively.…”

Fatty Acid and Water-Soluble Polymer-Based Controlled Release Drug Delivery System

“…Siepmann et al 7 provided a good review on how to use polymer blends as coating materials for controlled drug delivery systems. Karrout et al 8 explored novel polymeric film coatings for colonic drug delivery. One of the drawbacks of coating is that it is time-consuming and cannot be used for moisture sensitive drugs.…”

Colon Targeting of Naringin for Cytoprotection against Ulcerative Colitis: In Vitro-In Vivo Study

“…The local treatment of inflammatory bowel diseases, such as ulcerative colitis is highly challenging since it requires minimal release in the upper gastro-intestinal tract (GIT) and time-controlled release within the colon [14,15]. Coating of tablets with Eudragit-L100-55 (EUD-L) can protect the active drug from gastric fluid and possibly the proximal part of the small intestine [16].…”