Novel luminescent samarium(III) chelates

Development of luminescent Sm(III) chelates containing hexadentate to nonadentate ligands: synthesis, photophysical properties and coupling to biomolecules

“…These assays are based on energy transfer (TR-FRET) [7][8][9], quenching [6] or changes in the fluorescence properties of a chelate during reaction [10]. We have previously developed stable luminescent Sm(III) chelates [11] which enable multiparametric measurements even in homogeneous assays. Luminescent Sm chelates were used to label both peptides and oligonucleotides, and their usability was proved [11].…”

Lanthanide Nanoparticules as Photoluminescent Reporters

“…This is an advantage since the stability and water solubility requirements of the molecular lanthanide chelates are sometimes achieved at the cost of optimal photoluminescence properties. Moreover, lanthanide From [89]; other spectral characteristics from [90] chelate incorporated into nanoparticle reporters can enable a sensitive, quadruple label technology for applications requiring multiplexing and are more versatile labels for bioanalytical assays than luminescent molecular lanthanide chelates [91]. Another advantage of particulate lanthanide reporters is that they are potentially insensitive to the environment [92] unlike some of the intrinsically luminescent molecular chelates, which respond to other molecules in their proximate environment [26,93].…”

“…Some europium(III) chelate-dyed nanoparticles can even be excited above 400 nm wavelength [51,147,148], which, together with the development of UV-LED technology, may change the situation in the near future. Further advantage of UV-LED (and also N 2 laser) excitation is the rapid decay of the excitation pulse which, in the case of Xe flash lamps, can limit the detection of the very rapidly decaying emission of dysprosium(III) and samarium(III) [89] or of the energy-transfer excited emission with short apparent decay time in TR-FRET (time-resolved fluorescence resonance energy-transfer) applications [149].…”

The orange emission of single crystals and sol gels based on Sm3+ chelates

“…The design of efficient lanthanide complexes has become an important research goal, being published by several research groups [1][2][3][4][5]. The rare earth ions with ␤-diketones and their derivatives can also find potential application as NMR shifts reagents [5,6] as well as in bioscience [7]. Some important features of these organic fluorophores are their large Stokes' shift, narrow bands emission and long decay times [7].…”

“…The rare earth ions with ␤-diketones and their derivatives can also find potential application as NMR shifts reagents [5,6] as well as in bioscience [7]. Some important features of these organic fluorophores are their large Stokes' shift, narrow bands emission and long decay times [7]. Among all trivalent lanthanide ions complexes the studies were mainly focused on the europium and terbium ␤-diketones.…”