“…During voluntary muscle contractions, pools of spinal alpha-motoneurons (MNs) convert the synaptic input they receive into a neural command that drives the contractile activity of the innervated muscle fibres, determining limb motion. Identifying the recruitment and firing dynamics of MNs is fundamental for understanding the neural strategies controlling human voluntary motion, with applications in sport sciences (Felici & Del Vecchio, 2020; Watanabe, K. et al, 2021; Maeda et al, 2021), and neurological and musculoskeletal rehabilitation (Jordanić et al, 2016; Fang et al, 2020; Pilkar et al, 2020; Kisiel-Sajewicz et al, 2020; Nishikawa et al, 2021). Determining the MN-specific contributions to the MN population activity also allows more realistic control of neuromuscular models (Callahan et al, 2013; Potvin & Fuglevand, 2017; Kim & Kim, 2018; Carriou et al, 2019), investigation of muscle neuromechanics (Waasdorp et al, 2021; Martinez-Valdes et al, 2021), prediction of limb motion from MN-specific behaviour (Chen et al, 2020), or improvement in human-machine interfacing and neuroprosthetics (Farina et al, 2017; Farina et al, 2021).…”