Novel Coronavirus (COVID-19): Molecular Evolutionary Analysis, Global Burden and Possible Threat to Bangladesh

Abstract

Recently a new coronavirus strain, COVID-19 has emerged in Wuhan City, China which cause disease and in many cases deaths to humans. Considering its severity a number of works are working on it and full genomic sequences has already released in the last few weeks to understand the evolutionary origin and molecular characteristics of this virus. Based on currently available genomic information a phylogenetic tree was constructed from four types of representative viral proteins (Spike, Membrane, Envelope and Nucleoproetin) of COVID-19, HCoV-229E, HCoV-OC43, SARS-CoV, HCoV-NL63, HKU1, MERS-CoV, HKU4, HKU5 and BufCoV-HKU26 clearly demonstrated that the ancestral origin and distant evolutionary relation of newly epidemic novel coronavirus (COVID-19). It had been found that COVID-19 was evolutionary related to SARS-CoV. It was also found that COVID-19 proteins were almost more than ninety (90%) similar and identical with SARS-CoV proteins. The cross-checked conservancy analysis of COVID-19 antigenic epitopes showed significant conservancy with SARS-CoV proteins. VaxiJen server reveal almost 100% immunogenic potential of four viral proteins with COVID-19. In this article, we present an effort on molecular evolutionary analysis, temperature comparison and compile and analyze epidemiological outbreak information on the 2019 novel coronavirus based on the several open datasets on COVID-19 (SARS-COV-2) and possible threat to Bangladesh.Authors Md Bashir Uddin and Mahmudul Hasan contributed equally to this work

Impact of COVID-19 on the Indian seaport transportation and maritime supply chain

“…After initial exposure, the virus has quickly spread from China to various nations and territories around the world. The World Health Organization (WHO) has acknowledged the COVID-19 pandemic to be a public health emergency that predominantly affects human activities and economic development, and it is termed a quarantine situation ( Uddin et al, 2020 ; North, 2020 ). COVID-19 pandemic has spread across various nations and territories from the epicentre of Wuhan in China ( Ridruejo and Soza, 2020 ).…”

Socio-Demographic Depletion Due to COVID-19 Impact and Government Intervention: A Review in Bangladesh

“…Then it changed as a pandemic all over the world. Though a maximum number of cases were found in China then the virus was out broken, which began in Italy and expanded to the United States, France, Iran, Thailand, South Korea, Japan, and many other countries within a month, is shocking the entire world (Uddin et al, 2020).…”

Exploring the Impact of Covid 19 on the Maritime Transport Sector

“…The COVID-19 pandemic is spreading across the globe, affecting every element of modern life [1], Following the initial encounter, the virus rapidly migrated from China to other nations and regions throughout the globe. The COVID-19 pandemic has been deemed a public health emergency by the World Health Organization (WHO) that is primarily affecting human activities and economic development, and it has been categorized as a quarantine scenario by the WHO [2].…”