Novel Coronavirus: A New Challenge for Medical Scientist?

Ratan, Zubair Ahmed; Hosseinzadeh, Hassan; Runa, Nusrat Jahan; Uddin, Bhuiyan Mohammad Mahtab; Haidere, Mohammad Faisal; Sarker, Sujit Kumar; Zaman, Sojib Bin

doi:10.3329/bjid.v7i0.46805

Cited by 3 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The constant battle between viruses and scientists has been recognized as a key driver of medical advances. In this series of battles, the latest one is the outbreak of a novel coronavirus, COVID-19, originating in the Wuhan region of China in late December 2019 ( Ratan et al ., 2020 ). COVID-19 has affected at least 216 countries, areas or territories around the world.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Vaccine: Critical Questions with Complicated Answers

Haidere

Ratan

Nowroz

et al. 2021

Biomolecules & Therapeutics

Self Cite

View full text Add to dashboard Cite

COVID-19 has caused extensive human casualties with significant economic impacts around the globe, and has imposed new challenges on health systems worldwide. Over the past decade, SARS, Ebola, and Zika also led to significant concerns among the scientific community. Interestingly, the SARS and Zika epidemics ended before vaccine development; however, the scholarly community and the pharmaceutical companies responded very quickly at that time. Similarly, when the genetic sequence of SARS-CoV-2 was revealed, global vaccine companies and scientists have stepped forward to develop a vaccine, triggering a race toward vaccine development that the whole world is relying on. Similarly, an effective and safe vaccine could play a pivotal role in eradicating COVID-19. However, few important questions regarding SARS-CoV-2 vaccine development are explored in this review.

show abstract

Section: Introductionmentioning

confidence: 99%

COVID-19 Vaccine: Critical Questions with Complicated Answers

Haidere

Ratan

Nowroz

et al. 2021

Biomolecules & Therapeutics

Self Cite

View full text Add to dashboard Cite

show abstract

“…Vaccines have been proven to be the best approach for countering viral pandemics throughout human history [ 1 ]. The most recent viral pandemic is the ongoing COVID-19 pandemic, with the first cases reported in Wuhan, China, in December 2019 [ 2 ]. The pandemic triggered a global vaccine production race.…”

Section: Introductionmentioning

confidence: 99%

Qualitative Assessment of Early Adverse Effects of Pfizer–BioNTech and Sinopharm COVID-19 Vaccines by Telephone Interviews

et al. 2021

View full text Add to dashboard Cite

Vaccines are considered the best approach for countering the COVID-19 pandemic. In this study, we compared early side effects associated with vaccination with the Sinopharm and Pfizer–BioNTech COVID-19 vaccines. Participants of this observational cohort were interviewed based on semi-structured telephone interviews, with enquiries about side effects that developed after vaccination with each dose of these vaccines. Overall, 1004 participants were enrolled, of which 51.1% received Sinopharm vaccine and 48.9% received the Pfizer–BioNTech vaccine. After the first dose, 46.3% of participants had an adverse reaction, with injection site pain most commonly being reported (33.2%). Participants who received the Pfizer–BioNTech vaccine had significantly higher frequencies of all types of adverse reactions (p < 0.01), with no significant differences in the duration of adverse reactions between the two vaccines. Regarding the second dose, 48.6% of participants had adverse reactions, with injection site pain being most commonly reported (29%). Those who received the Pfizer vaccine reported higher frequencies of all adverse reactions (p < 0.01). However, a longer duration of adverse reactions was seen among Sinopharm vaccine recipients as compared to Pfizer–BioNTech vaccine recipients (p = 0.01). In conclusion, early adverse effects are reported following all types of vaccines but these are more likely to be encountered following the administration of new-generation vaccines. These side effects are mostly mild and treatable.

show abstract