2022
DOI: 10.3390/toxins14050342
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Novel Anatomical Guidelines on Botulinum Neurotoxin Injection for Wrinkles in the Nose Region

Abstract: Botulinum neurotoxin injection surrounding the nose area is frequently used in aesthetic settings. However, there is a shortage of thorough anatomical understanding that makes it difficult to treat wrinkles in the nose area. In this study, the anatomical aspects concerning the injection of botulinum neurotoxin into the nasalis, procerus, and levator labii superioris alaeque muscles are assessed. In addition, the present knowledge on localizing the botulinum neurotoxin injection point from a newer anatomy study… Show more

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Cited by 19 publications
(17 citation statements)
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“…Facial aging is characterized by wrinkles, sagging skin, and a decrease in the amount of fat and elasticity in the face, particularly in the cheeks and surrounding tissue, which usually results in subzygomatic arch depression (Rewari et al, 2020). Wrinkles can be treated using botulinum neurotoxin injections, however, volume loss caused by the aging process is primarily treated with dermal filler injections (Yi et al, 2021; Yi, Lee, Hu, & Kim, 2022a, 2022b; Yi, Lee, Kim, Yoon, et al, 2022; Yi, Lee, Lee, Hu, et al, 2022). Subzygomatic arch depression may result in an appearance of premature aging and fatigue resulting from zygomatic arch and zygoma protrusion.…”
Section: Discussionmentioning
confidence: 99%
“…Facial aging is characterized by wrinkles, sagging skin, and a decrease in the amount of fat and elasticity in the face, particularly in the cheeks and surrounding tissue, which usually results in subzygomatic arch depression (Rewari et al, 2020). Wrinkles can be treated using botulinum neurotoxin injections, however, volume loss caused by the aging process is primarily treated with dermal filler injections (Yi et al, 2021; Yi, Lee, Hu, & Kim, 2022a, 2022b; Yi, Lee, Kim, Yoon, et al, 2022; Yi, Lee, Lee, Hu, et al, 2022). Subzygomatic arch depression may result in an appearance of premature aging and fatigue resulting from zygomatic arch and zygoma protrusion.…”
Section: Discussionmentioning
confidence: 99%
“…1 Non-invasive cosmetic procedures, such as thread lifting, dermal fillers and botulinum neurotoxin injections, have been proven to effectively address these issues. [2][3][4][5][6] Thread lifting, in particular, utilizes threads composed of materials such as polydioxanone (PDO), poly-L-lactic acid (PLLA) and etc. to lift and tighten sagging skin on the face.…”
Section: Introductionmentioning
confidence: 99%
“…Intramuscular distribution‐based injections have demonstrated superior effectiveness in clinical studies of the biceps brachii and psoas major muscles, with a much higher volume reduction than that in the control group (Gracies et al, 2009; Van Campenhout et al, 2013). There have been many articles published to suggest injection points using BoNT (Yi et al, 2020; Yi, Lee, Hu, & Kim, 2022; Yi, Lee, Hur, Seo, & Kim, 2022; Yi, Lee, Kim, Yoon, et al, 2022; Yi, Lee, Seo, & Kim, 2022b).…”
Section: Introductionmentioning
confidence: 99%